331765-59-4

Upstream product

• 159635-49-1 tert-butyl 4-methylidenepiperidine-1-carboxylate 
• 331765-58-3 C₁₂H₈BrClO₂S 

Downstream Products

• 331765-60-7 4-[4-(3-chloro-benzenesulfonyl)-benzyl]-piperidine 
• 331765-61-8 4-[4-(3-chloro-benzenesulfonyl)-benzyl]-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester 
• 331765-62-9 4-[4-(3-chloro-benzenesulfonyl)-benzyl]-[1,4']bipiperidinyl 
• 331765-50-5 Sch 211803 

Relevant academic research and scientific papers

MUSCARINIC ANTAGONISTS

Amide derivatives of 1,4 di-substituted piperidine compounds of formula (I) or a pharmaceutically acceptable salt, ester or solvate thereof, wherein Q and Q are each -CH=, or one of Q and Q is -CH= and the other is -N=; X is -CH2- or (a); Y and Z are -C(R)=, or one of Y and Z is -C(R)= and the other is -N=; R is 1 to 3 substituents selected from H, halogen and alkoxy; R and R are 1 to 3 substituents selected from H, halogen, alkyl and alkoxy; and R and R are H or (C1-C6) alkyl are muscarinic antagonists usuful for treating cognitive disorders such as Alzheimer's disease. Pharmaceutical compositions and methods of preparation are also disclosed.