331767-61-4

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 331767-53-4 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid chloride 

Downstream Products

• 331767-37-4 9-{4-[4-(6-methoxy-pyridin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-4-methoxybenzyl-amide 
• 348134-30-5 9-[4-(4-quinazolin-2-yl-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-4-methoxy-benzylamide 
• 348134-35-0 9-[4-(4-benzothiazol-2-yl-[1.4]diazepan-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-4-methoxy-benzylamide 
• 348134-28-1 9-[4-(4-quinolin-2-yl-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-4-methoxy-benzylamide 
• 348134-32-7 9-[4-(4-benzothiazol-2-yl-piperazin-1-yl)-butyl]-9H-fluorene-9-carboxylic Acid-4-methoxy-benzylamide 

Relevant academic research and scientific papers

Substituted piperazine derivatives, the preparation thereofand their use as medicaments

The present invention relates to substituted piperazine derivatives of general formula , (I wherein Ra, Rb, Rc, Rf, Rg, X, m and n are defined as in claim 1, the isomers and salts thereof, particularly the physiologically acceptable salts thereof, which are valuable inhibitors of the microsomal triglyceride-transfer protein (MTP), medicaments containing these compounds and their use, as well as the preparation thereof.