331808-81-2 Usage
Uses
Used in Pharmaceutical Industry:
2-(N-2-chlorobenzoyl)amino-5-aminopyrimidine is used as a chemical precursor for the synthesis of various drugs and medicines. Its versatile chemical structure allows for the development of new pharmaceutical formulations with potential therapeutic effects.
Used in Drug Development:
Due to its potential biological activities and therapeutic effects, 2-(N-2-chlorobenzoyl)amino-5-aminopyrimidine is studied for its applications in the treatment of various diseases and conditions. Its unique chemical properties make it a promising candidate for the development of new medications with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 331808-81-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,1,8,0 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 331808-81:
(8*3)+(7*3)+(6*1)+(5*8)+(4*0)+(3*8)+(2*8)+(1*1)=132
132 % 10 = 2
So 331808-81-2 is a valid CAS Registry Number.
331808-81-2Relevant academic research and scientific papers
Therapeutic quinazoline derivatives
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, (2008/06/13)
A compound of formula (I) or a salt, ester, amide or prodrug thereof; where X is O, or S, S(O), S(O)2 or NR6 where R6 is hydrogen of C1-6alkyl; R5 is an optionally substituted 6-membered aromatic ring containing at least one nitrogen atom, and R1, R2, R3, R4 are independently selected from halogeno, cyano, nitro, C1-3alkylsulphanyl, —N(OH)R7— (wherein R7 is hydrogen, or C1-3alkyl), or R9X1— (wherein X1 represents a direct bond, —O—, —CH2—, —OC(O), —C(O)—, —S—, —SO—, —SO2—, —NR10C(O)—, —C(O)NR11—, —SO2NR12—, —NR13SO2— or NR14— (wherein R10, R11, R12, R13 and R14 each independently represents hydrogen, C1-3alkyl or C1-3alkoxyC2-3alkyl), and R9 is hydrogen, optionally substituted hydrocarbyl, optionally substituted heterocyclyl or optionally substituted alkoxy; provided that at least one of R2 or R3 is other than hydrogen. These compounds inhibit aurora 2 kinase and are useful in the preparation of medicaments for the treatment of proliferative disease such as cancer.
