331862-83-0Relevant academic research and scientific papers
Design, biological evaluation and 3D QSAR studies of novel dioxin-containing triaryl pyrazoline derivatives as potential B-Raf inhibitors
Yang, Yu-Shun,Yang, Bing,Zou, Yan,Li, Guigen,Zhu, Hai-Liang
, p. 3052 - 3061 (2016/06/13)
A series of novel dioxin-containing triaryl pyrazoline derivatives C1-C20 have been synthesized. Their B-Raf inhibitory and anti-proliferation activities were evaluated. Compound C6 displayed the most potent biological activity against B-RafV600E/su
