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Upstream product

• 399511-15-0 L-glycero-2,3-dihydroxy-2,3-O-isopropylidenepropyl 4-O-benzyl-2,3-di-O-(2,3-dimethoxybutane-2,3-diyl)-5a-carba-α-L-fucopyrnaoside 
• 399510-98-6 4-O-benzyl-2,3-O-(2,3-dimethoxybutane-2,3-diyl)-5a-carba-α-L-fucopyranose 

Relevant academic research and scientific papers

The conformational behaviour of fucosyl and carbafucosyl mimetics in the free and in the protein-bound states

The conformational behaviours of fucosyl glycosides bearing a glyceryl aglycon and their corresponding carbafucosyl glycomimetics have been studied both in aqueous solution and when bound to a fucose-specific lectin (Aurelia Aurantia Agglutinnin), using a combination of NMR spectroscopy (J and NOE data) and molecular mechanics calculations. Analogies and differences between the mimetics and the natural compounds have been found.

Synthesis of carba- and C-fucopyranosides and their evaluation as α-fucosidase inhibitors - Analysis of an unusual conformation adopted by an amino-C-fucopyranoside

Several carba- and C-fucopyranosides bearing a variety of substituents at their pseudoanomeric positions have been synthesized and tested as inhibitors of bovine kidney a-fucosidase. From the IC50 values, some conclusions about the structure-ac