331991-08-3Relevant academic research and scientific papers
Reactive Ketenes through a Carbonate/Amine Shuttle Deprotonation Strategy: Catalytic, Enantioselective α-Bromination of Acid Chlorides
Hafez, Ahmed M.,Taggi, Andrew E.,Wack, Harald,Esterbrook, Julie,Lectka, Thomas
, p. 2049 - 2051 (2007/10/03)
We have developed an efficient methodology for the generation of ketenes by employing a catalytic shuttle base and potassium carbonate as a stoichiometric base. We have applied this technology to the catalytic, asymmetric α-bromination of acid chlorides.
