332-97-8 Usage
Chemical compound
8-Fluorooctanoic acid ethyl ester
Main use
Surfactant or wetting agent
Derived from
8-fluorooctanoic acid
Properties
1. Repels water and oil
2. Ethyl ester form
3. Industrial applications:
Production of coatings
Production of adhesives
Production of lubricants
Manufacturing of polymers
Manufacturing of plastics
Concerns
1. Potential toxicity
2. Environmental impact
3. Persistence in the environment
4. Potential for bioaccumulation in living organisms
Ongoing
1. Research
2. Regulation
3. Use and disposal management
Check Digit Verification of cas no
The CAS Registry Mumber 332-97-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,3 and 2 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 332-97:
(5*3)+(4*3)+(3*2)+(2*9)+(1*7)=58
58 % 10 = 8
So 332-97-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H19FO2/c1-2-13-10(12)8-6-4-3-5-7-9-11/h2-9H2,1H3
332-97-8Relevant articles and documents
SITE-SPECIFIC RADIOFLUORINATION OF PEPTIDES WITH 8-[18F]-FLUOROOCTANOIC ACID CATALYZED BY LIPOIC ACID LIGASE
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, (2017/12/28)
New methodologies for site-specifically radiolabeling proteins with the PET isotope [18F] are required to generate high quality radiotracers for imaging in both the preclinical and clinical settings. The enzymatic radiofluorination overcomes many of the limitations encountered to date with purely chemical approaches. The bacterial enzyme lipoic acid ligase was used to conjugate [18F]-fluorooctanoic acid to both a small peptide and a Fab antibody fragment. Labeling was site-specific and highly efficient under mild aqueous conditions using small amounts of peptide/protein (1-10 nmol). The labeled construct retained full epitope binding affinity and was stable in mouse serum. Using an optimized reaction scheme, mCi quantities of [18F]-Fab were generated, an amount sufficient for human imaging.
