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332016-46-3

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332016-46-3 Usage

Appearance

White to light yellow crystalline

Usage

Pharmaceutical development, research and development, building block/intermediate in organic synthesis

Therapeutic potential

Interaction with biological targets, key component in medicinal chemistry and drug discovery

Safety precautions

Handle with caution, follow proper safety protocols due to potential hazards and risks

Check Digit Verification of cas no

The CAS Registry Mumber 332016-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,2,0,1 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 332016-46:
(8*3)+(7*3)+(6*2)+(5*0)+(4*1)+(3*6)+(2*4)+(1*6)=93
93 % 10 = 3
So 332016-46-3 is a valid CAS Registry Number.

332016-46-3Relevant articles and documents

N-transfer reagent and method for preparing the same and its application

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Page/Page column 23-24, (2021/06/25)

Provided are a novel N-transfer reagent and a method for preparing the same and its application. The N-transfer reagent is represented by the following Formula (I): The various novel N-transfer reagents of the present invention can be quickly prepared by employing different nitrobenzene precursors. The N-transfer reagents can directly convert a variety of amino compounds into diazo compounds under mild conditions. Particularly, the N-transfer reagents can facilitate the synthesis of the diazo compounds. The application of synthesizing diazo compounds of the present invention can greatly decrease the difficulty in operation, increase the safety during experiments, reduce the cost of production and the environmental pollution, and enhance the industrial value of diazo compounds.

Synthesis and anticonvulsant activity of some N-(benzoyl)glycinanilide derivatives

Soyer, Zeynep,Akgul, Ozlem,Tarikogullari, Ayse H.,Calis, Unsal

, p. 4708 - 4714 (2013/09/23)

Glycine is a major inhibitory neurotransmitter and recent studies have shown that certain lipophilic glycine derivatives demonstrate anticonvulsant activity in animal epilepsy models. On the other hand, anilide is another fruitful structure for designing potential anticonvulsant agents. Ameltolide, ralitoline and some phthalimide derivatives are the examples of anilide analogs with potent anticonvulsant activity. In this study, two key structural pharmacophores were combined and a series of N-benzoylglycinanilide derivatives were designed. Their anticonvulsant activities evaluated against maximal electroshock (MES) and subcutaneous metrazole seizure tests, whereas their neurotoxicity was examined by rotarod test. The preliminary screening results indicated that majority of the compounds were effective in the MES test. None of the compounds showed neurotoxicity according to the rotarod test at studied doses. The most active compound in the series is N-(2-((4-methoxyphenyl)amino)- 2-oxoethyl)benzamide (compound 8) which bearing 4-methoxy substituent on the N-phenyl ring.

Convenient synthesis of a new class of N2SO or N2S2 tetradentate ligands suitable for nuclear medicine applications

Fourteau,Benoist,Dartiguenave

, p. 126 - 128 (2007/10/03)

In our search for a 99mTc labelled brain perfusion imaging agent, six new tetradentate acyclic ligands have been synthesised in good yield, through easy and fast syntheses. These compounds possess an aromatic ring bridging a nitrogen and an oxygen or a sulfur and contain two amides (1a, 1b) or an amine and an amide functionalities (2a-2d), which make them good candidates for radiopharmaceuticals.

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