33209-85-7Relevant academic research and scientific papers
Reactions of N-Aminopyrazoles with Halogenating Reagents and Synthesis of 1,2,3-Triazines
Ohsawa, Akio,Kaihoh, Terumitsu,Itoh, Takashi,Okada, Mamiko,Kawabata, Chikako,et al.
, p. 3838 - 3848 (2007/10/02)
Reactions of N-aminopyrazoles with halogenating reagents (Cl2, Br2, I2, BrCl, ICl, IBr, N-chlorosuccinimide, and N-bromosuccinimide) were examined.Some of these reagents preferentially lead to oxidation of the amino group to give the corresponding 1,2,3-triazines as major products, while others mainly gave either or both of 1-amino-4-halopyrazoles and 5-halo-1,2,3-triazines as the result of halogenation of the 4-position of the pyrazole ring prior to the oxidation of the amino group.In some cases, the oxidation of the amino group and the halogenation of the pyrazole ring proceeded concurrently to form not only the unhalogenated triazines but also the 1-amino-4-halopyrazoles and the 5-halotriazines.Various reagents and reaction conditions were explored to utilize the reaction for the synthesis of halogenated and unhalogenated 1,2,3-triazines.Keywords - 1,2,3-triazine; halo-1,2,3-triazine; pyrazole; 1-aminopyrazole; 1-aminohalopyrazole; synthesis; oxidation; halogenation; ring expansion
Oxidation of 1-Aminopyrazoles and Synthesis of 1,2,3-Triazines
Ohsawa, Akio,Arai, Heihachiro,Ohnishi, Hidefumi,Itoh, Takashi,Kaihoh, Terumitsu,et al.
, p. 5520 - 5523 (2007/10/02)
Unsubstituted and various substituted monocyclic 1,2,3-triazines were synthesized from 1-aminopyrazoles by oxidation with lead tetraacetate, lead dioxide-CF3CO2H, and/or nickel peroxide-AcOH.
1,2,3-Triazines,III. - Synthesis of N-Aminopyrazoles and their Oxidation to 1,2,3-Triazines. Molecular Structure of 1,2,3-Triazine
Neunhoeffer, Hans,Clausen, Monika,Voetter, Hans-Dieter,Ohl, Harald,Krueger, Carl,Angermund, K.
, p. 1732 - 1751 (2007/10/02)
Oxidation of the N-aminopyrazoles 4a-i affords the 1,2,3-triazines 5a-i.Spectra and reactions - such as oxidation, reduction, and cycloaddition reactions - of some 1,2,3-triazines 5 are described.The X-ray analysis of 5a is presented.
Synthesis, Oxidation, and Reduction of Monocyclic 1,2,3-Triazines
Ohsawa, Akio,Arai, Heihachiro,Ohnishi, Hidefumi,Igeta, Hiroshi
, p. 1182 - 1183 (2007/10/02)
Alkyl substituted monocyclic 1,2,3-triazines and their 1- and 2-oxides have been synthesized; catalytic reduction (on Pd-C) of the triazines afforded their 2,5-dihydro compounds.
