332113-62-9Relevant academic research and scientific papers
Evaluation of P1'-Diversified Phosphinic Peptides Leads to the Development of Highly Selective Inhibitors of MMP-11
Matziari, Magdalini,Beau, Fabrice,Cuniasse, Philippe,Dive, Vincent,Yiotakis, Athanasios
, p. 325 - 336 (2007/10/03)
Phosphinic peptides were previously reported to be potent inhibitors of several matrixins (MMPs). To identify more selective inhibitors of MMP-11, a matrixin overexpressed in breast cancer, a series of phosphinic pseudopeptides bearing a variety of P
Convenient synthesis and diversification of dehydroalaninyl phosphinic peptide analogues.
Matziari,Georgiadis,Dive,Yiotakis
, p. 659 - 662 (2007/10/03)
[structure: see text]. Dehydroalaninyl phosphinic dipeptide analogues were synthesized, via an efficient tandem Arbuzov addition/allylic rearrangement, in high yields. The susceptibility of the conjugate system to 1,4 nucleophilic additions was investigat
