TAN 1364B, also known as CI 010, is a monomeric sub-unit of the tetronic acid complex isolated from Streptomyces. It is often mis-named as RK-682 by many suppliers due to confusion about the structure of RK-682, which is a dimeric calcium complex of the major analogue of the tetronic acid complex. TAN 1364B is chemically defined as 3-hexadecanoyl-5-hydroxymethyltetronic acid.
Source:
TAN 1364B is originally isolated from the fermentation of Streptomyces sp. 88-682.
Production Methods:
The specific production methods for TAN 1364B are not provided in the materials.
Source:
TAN 1364B is originally isolated from the fermentation of Streptomyces sp. 88-682.
Production Methods:
The specific production methods for TAN 1364B are not provided in the materials.
332131-32-5
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Basic information
- Product Name: TAN 1364B, CI 010
- Synonyms: TAN 1364B, CI 010;RK-682 (calcium salt)
- CAS NO:332131-32-5
- Molecular Formula: C42H72CaO10+2
- Molecular Weight: 777.09308
- EINECS: N/A
- Product Categories: N/A
- Mol File: 332131-32-5.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: TAN 1364B, CI 010(CAS DataBase Reference)
- NIST Chemistry Reference: TAN 1364B, CI 010(332131-32-5)
- EPA Substance Registry System: TAN 1364B, CI 010(332131-32-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 332131-32-5(Hazardous Substances Data)
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332131-32-5 Usage
Uses
Used in Pharmaceutical Industry:TAN 1364B, CI 010 is used as an inhibitor of protein tyrosine phosphatases (PTPs) for its role in regulating cell growth, proliferation, differentiation, survival or apoptosis, adhesion, and motility. It is also used as a specific inhibitor of PTP1B.
Used in Anti-cancer Applications:
TAN 1364B, CI 010 is used as a potential anti-cancer agent, as it can inhibit the activity of various enzymes, including heparanase and HIV-1 protease, which are involved in tumor cell invasion and angiogenesis.
Used in Enzyme Inhibition:
TAN 1364B, CI 010 is used as an inhibitor of phospholipase A2, an enzyme involved in the production of inflammatory mediators, and heparinase, an enzyme involved in the degradation of heparin sulfate proteoglycans.
Note: The materials provided do not mention the use of TAN 1364B, CI 010 as a drug delivery system or its synergistic effects with conventional chemotherapeutic drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 332131-32-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,2,1,3 and 1 respectively; the second part has 2 digits, 3 and 2 respectively.Calculate Digit Verification of CAS Registry Number 332131-32:
(8*3)+(7*3)+(6*2)+(5*1)+(4*3)+(3*1)+(2*3)+(1*2)=85
85 % 10 = 5
So 332131-32-5 is a valid CAS Registry Number.
332131-32-5Upstream product
332131-32-5Downstream Products
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TAN 1364B, CI 010
