332143-52-9Relevant academic research and scientific papers
Total synthesis of mappicine ketone (nothapodytine B) by means of sulfur-directed 5-exo-selective aryl radical cyclization onto enamides
Kato, Issei,Higashimoto, Masayuki,Tamura, Osamu,Ishibashi, Hiroyuki
, p. 7983 - 7989 (2007/10/03)
Enamides 5, on treatment with Bu3SnH-AIBN, underwent aryl radical cyclization in a 5-exo manner to give 1-[bis(phenylthio)methyl]dihydroisoindoles 6, which were partially desulfurized with Bu3SnH-AIBN to give 1-mono(phenylthio)methyl
Synthesis of a model compound of mappicine ketone based on sulfur-directed 5-exo selective aryl radical cyclization onto enamides
Ishibashi, Hiroyuki,Kato, Issei,Takeda, Yoshifumi,Tamura, Osamu
, p. 931 - 933 (2007/10/03)
Enamides 10, upon treatment with Bu3SnH-AIBN, gave 5-exo aryl radical cyclization products 11, which were partially dusulfurized to give 1-substituted dihydroisoindoles 7 and 12. This method was applied to the synthesis of a model compound 4 of
