33224-62-3Relevant academic research and scientific papers
Reductive cleavage of the Csp2-Csp3 bond of secondary benzyl alcohols: Rhodium catalysis directed by N-containing groups
Chen, Kang,Li, Hu,Lei, Zhi-Quan,Li, Yang,Ye, Wen-He,Zhang, Li-Sheng,Sun, Jian,Shi, Zhang-Jie
, p. 9851 - 9855 (2012)
Cutting loose: 1,1-Biarylmethanol substrates undergo reductive cleavage of the C-C bond in the presence of a cationic RhIII catalyst and H 2 (see scheme; DG=directing group). Various functional groups are tolerated in the reaction system. Preliminary studies indicate that a five-membered rhodacycle intermediate, which then converts into a Rh III hydride species for the reduction, is involved in the catalytic cycle. Copyright
