3323-02-2 Usage
Uses
Used in Pharmaceutical Development:
2-(p-Methoxyphenyl)-3-(morpholinomethyl)imidazo[1,2-a]pyridine is utilized as a chemical entity in the development of new pharmaceuticals, leveraging its imidazopyridine structure to target specific biological pathways or receptors. Its unique functional groups may contribute to its interaction with biological targets, offering a new avenue for therapeutic intervention.
Used in Pharmacological Research:
In the field of pharmacology, 2-(p-Methoxyphenyl)-3-(morpholinomethyl)imidazo[1,2-a]pyridine serves as a research tool to explore the mechanisms of action, efficacy, and safety of imidazopyridine-based compounds. It can be employed in various assays and models to understand its potential as a lead compound for drug discovery.
Used in Medicinal Chemistry:
2-(p-Methoxyphenyl)-3-(morpholinomethyl)imidazo[1,2-a]pyridine is applied in medicinal chemistry for the synthesis of analogs and derivatives with improved pharmacological properties. Its structural features can be modified to optimize drug-like characteristics, such as potency, selectivity, and pharmacokinetics, which are essential for the advancement of drug candidates.
Used in Drug Discovery:
2-(p-Methoxyphenyl)-3-(morpholinomethyl)imidazo[1,2-a]pyridine is used as a starting point in drug discovery for the identification of novel therapeutic agents. Its imidazopyridine core and substituents can be fine-tuned to enhance its biological activity, making it a promising candidate for the treatment of various diseases and conditions.
Used in Chemical Synthesis:
In the realm of chemical synthesis, 2-(p-Methoxyphenyl)-3-(morpholinomethyl)imidazo[1,2-a]pyridine is employed as a building block or intermediate in the preparation of more complex organic molecules. Its unique structure can be further functionalized or modified to create a diverse range of compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 3323-02-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,3,2 and 3 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3323-02:
(6*3)+(5*3)+(4*2)+(3*3)+(2*0)+(1*2)=52
52 % 10 = 2
So 3323-02-2 is a valid CAS Registry Number.
InChI:InChI=1/C19H21N3O2/c1-23-16-7-5-15(6-8-16)19-17(14-21-10-12-24-13-11-21)22-9-3-2-4-18(22)20-19/h2-9H,10-14H2,1H3
3323-02-2Relevant articles and documents
Use of imidazo[1,2-a]pyridine as a carbonyl surrogate in a mannich-like, catalyst free, one-pot reaction
Naresh, Gunaganti,Lakkaniga, Naga Rajiv,Kharbanda, Anupreet,Yan, Wei,Frett, Brendan,Li, Hong-Yu
, p. 770 - 777 (2019/01/14)
Derivatization of imidazo[1,2-a]pyridine scaffolds have gained considerable attention due to the biological significance of therapeutics based on the imidazopyridine core. By utilizing a catalyst-free, “Mannich type” reaction, we developed a simple and efficient protocol to aminomethylate the C-3 position of imidazo[1,2-a]pyridine through a multicomponent, de-carboxylation reaction involving imidazo[1,2-a]pyridine, a secondary amine, and glyoxylic acid. The developed protocol re-quires mild reaction conditions and furnishes diverse imid-azo[1,2-a]pyridine analogues from commercially available starting materials. Additionally, the current protocol improves prior methods, which were limited by the amine substrate scope. Taken together, this current methodology permits rapid diversification of imidazo[1,2-a]pyridines to enhance combinatorial efficiency in the drug discovery processes.
Aminomethylation of Imidazoheterocycles with Morpholine
Mondal, Susmita,Samanta, Sadhanendu,Singsardar, Mukta,Hajra, Alakananda
supporting information, p. 3751 - 3754 (2017/07/26)
A hitherto unreported aminomethylation occurs at C-3 of imidazopyridines with morpholine in the presence of (diacetoxyiodo)benzene at ambient temperature in short reaction times. This methodology is also applicable to indolizine, imidazo[2,1-b]thiazole, benzo[d]imidazo[2,1-b]thiazole, and indole. Interestingly, the aminomethylation involving morpholine as a source of methylene group is a new phenomenon. This protocol is of much potential for the synthesis of aminomethylated derivatives under mild reaction conditions.
