33238-73-2Relevant academic research and scientific papers
Synthesis and anticonvulsant activity of acetylenic quinazolinone derivatives
Usifoh, Cyril O.,Scriba, Gerhard K. E.
, p. 261 - 266 (2000)
Acetylenic derivatives of quinazolinones and quinazolinediones were synthesized and evaluated for their anticonvulsant activity. Most compounds displayed seizure-antagonizing activity in the maximal electroshock test (MES test) in most cases associated wi
Acetylenic Chemistry: Part 13. Synthesis of Oxazoles and Oxazoloquinazolines from o-Amino-N-(1,1-disubstituted-propynyl)benzamide
Reisch, J.,Usifoh, C. O.,Oluwadiya, J. O.
, p. 1495 - 1498 (2007/10/02)
Convertion of isatoic anhydride to o-amino-N-(1,1-disubstituted-propynyl)benzamides 3a-c followed by reflux in ethanolic potassium hydroxide gave 2-(o-aminophenyl)-4,4-disubstituted-5-methylene-4H-oxazoles 4a-c.The treatment of same 3a-c with triphosgene
