33238-93-6

Usage

InChI:InChI=1/C15H12N2O/c18-15-13(11-7-3-1-4-8-11)14(16-17-15)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18)

Upstream product

• 886-38-4 diphenylcyclopropenone 
• 58929-02-5 ethyl 2,3-diphenyl-3-oxopropanoate 
• 306279-95-8 camphoric acid 
• 97978-59-1 3-ethoxy-4,5-diphenyl-1H-pyrazole 
• 1194790-85-6 methyl 4,5-diphenyl-3-oxo-2,3-dihydro-1H-pyrazole-1-carboxylate 
• 18795-79-4 (±)-4,5-diphenylpyrazolidin-3-one 

Relevant academic research and scientific papers

[3 + 2]-Cycloadditions of Azomethine Imines and Ynolates

A novel [3 + 2]-cycloaddition between azomethine imines and lithium ynolates is described to synthesize bicyclic pyrazolidinones. These bicyclic pyrazolidinones are versatile intermediates to form β-amino acids and monocyclic pyrazolidinones. High diaster

Alkoxypyrazoles and the process for their preparation

The present invention relates to a alkoxypyrazoles preparation process, and new alkoxypyrazole compounds.

A simple approach to pyrazol-3-ones via diazenes

An efficient entry into pyrazol-3-ones is described starting from propenoic acids that were first transformed into the corresponding hydrazides. Oxidation of the hydrazides gave the diazenes and the latter cyclized to pyrazol-3-ones on treatment with ZrCl4. The methoxycarbonyl protection of the N-1 of the pyrazolone derivatives was easily removed under mild reaction conditions.

4-Arylation of 3-alkoxypyrazoles

Following the study of the alkoxypyrazoles nitrogen's reactivity toward arylation or alkylation reactions, we report here our results on the introduction of various aryl groups on carbon 4 position of 3-alkoxypyrazoles. This was achieved from the correspo

Synthesis and biological activity of N,N-dialkylaminoalkyl-substituted bisindolyl and diphenyl pyrazolone derivatives

New compounds, structurally related to the potent protein kinase C inhibitor staurosporine, with a bisindolylpyrazolone framework and substituted on the pyrazolone nitrogens with N,N-dialkylaminoalkyl side chain, were synthesized and evaluated for growth-

Pyrazole antimicrobial agents

The present invention provides pyrazole and pyrazolone derivatives. Preferred compounds of the invention are useful as RNA polymerase inhibitors. Further preferred compounds of the invention are useful as antimicrobial agents.

N-(heterocycle)alkyl)-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use

N-[(heterocycle)alkyl]-3,4 (or 4,5)-diaryl-1H-pyrazole-1-acetamides and pyrazole-1-propanamides, useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl ester of pyrazole-1-acetic or propanoic acid with an appropriate (heterocycle-alkyl) amine or by reacting a pyrazole-1-acetic or propanoic acid with an appropriate (heterocycle-alkyl)amine.

1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use

N-[(disubstituted amino)alkyl]-3,4 (or 4,5)-diaryl-1H-pyrazole-1-acetamides and pyrazole-1-propanamides, useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl ester of pyrazole-1-acetic or propanoic acid with an appropriate diamine or by reacting a lower-alkyl ester of a pyrazole-1-acetic or propanoic acid with an ω-aminoalkanol, followed by activation of the alcohol and displacement by an appropriate amine.

REACTIONS OF DIPHENYLCYCLOPROPENONE WITH HYDRAZINE DERIVATIVES: FORMATION OF PYRAZOLONE DERIVATIVES VIA 3-AMINOCINNAMOHYDRAZIDES

Reactions of diphenylcyclopropenone (1) with hydrazine or phenylhydrazine gave ring opening products (4,5-diphenylpyrazolones, 3) via 3-aminocinnamohydrazide derivatives (4).However, hydrazones (2) were obtained, in general, with 1 and hydrazine derivativ