33240-23-2Relevant articles and documents
Design, synthesis, and biological evaluation of AV6 derivatives as novel dual reactivators of latent HIV-1
Ao, Mingtao,Pan, Zhenrui,Qian, Yuqing,Tang, Bowen,Feng, Zeming,Fang, Hua,Wu, Zhen,Chen, Jingwei,Xue, Yuhua,Fang, Meijuan
, p. 17279 - 17292 (2018)
The "shock and kill" strategy might be a promising therapeutic approach for HIV/AIDS due to the existence of latent viral reservoirs. A major challenge of the "shock and kill" strategy arises from the general lack of clinically effective latency-reversing
Multicomponent reaction for the synthesis of highly functionalized piperidine scaffolds catalyzed by TMSI
Wu, Lisha,Yan, Shiqiang,Wang, Wensheng,Li, Yinta
, p. 4311 - 4322 (2020/07/13)
An efficient method for the synthesis of highly functionalized piperidines via one-pot domino reaction of β-ketoesters, aromatic aldehydes, and aromatic amines was reported. This multicomponent coupling was catalyzed by TMSI in methanol at room temperature, giving desired substituted pyridines in moderate to good yields.
Highly efficient and facile synthesis of β-enaminones catalyzed by diphenylammonium triflate
Zhao, Ting-Ting,Song, Jiang-Long,Hong, Feng-Qing,Xia, Jian-Sheng,Li, Jian-Jun
, p. 2857 - 2868 (2019/08/21)
Abstract: The catalytic performance of diphenylammonium triflates as an organocatalyst in the synthesis of β-enaminones from various substituted β-diketones and amides (or amines) were evaluated. A wide range of β-enaminones were efficiently synthesized in good to excellent yields under mild reaction conditions. Applying diphenylammonium triflate (DPAT) as catalyst makes this protocol cost-effective, low corrosive and easy to handle. Graphic abstract: [Figure not available: see fulltext.].