33259-07-3Relevant academic research and scientific papers
Rhodium-Catalyzed Asymmetric Hydrogenation of 3-Benzoylaminocoumarins for the Synthesis of Chiral 3-Amino Dihydrocoumarins
Xu, Yunnan,Liu, Delong,Deng, Yu,Zhou, Yi,Zhang, Wanbin
supporting information, p. 23602 - 23607 (2021/10/05)
An asymmetric hydrogenation of 3-benzoylaminocoumarins was achieved for the first time using our BridgePhos-Rh catalytic system, providing chiral 3-amino dihydrocoumarins in high yields (up to 98 %) and with excellent enantioselectivities (up to 99.7 % ee). The relationship between the enantioselectivities of the hydrogenations and the dihedral angles and the resulting π-π stacking effects of the BridgePhos-Rh complexes, which were determined by X-ray diffraction analysis, are discussed. The corresponding hydrogenated products allow for many transformations, providing several chiral skeletons with important physiological and pharmacological activities.
A one-pot [Bmim]OH-mediated synthesis of 3-benzamidocoumarins
Yadav, Lal Dhar S.,Singh, Santosh,Rai, Vijai K.
experimental part, p. 2208 - 2212 (2009/08/07)
The first example of an ionic liquid-promoted one-pot synthesis of 3-benzamidocoumarins from salicylaldehydes and 2-pheny-1,3-oxazolan-5-one via Knoevenagel condensation-ring transformation cascades has been reported. No by-product formation, operational
Synthesis of 2-methyl-9-oxo-9H-furo[2,3-c]benzo pyrans and 2-methyl- 3H,4H[1]benzopyrano[3,4-b]pyrrol-4-ones
Raghu Ram,Krupadanam,Srimannarayana
, p. 2421 - 2428 (2007/10/03)
3:4-Fused furocoumarins and pyrrolocoumarins are synthesised from 3- hydroxy and 3-benzamido- substituted coumarins by a novel two step sequence.
