33262-29-2Relevant academic research and scientific papers
Preparative supercritical deuterium exchange in arenes and heteroarenes
Junk, Thomas,Catallo, W. James
, p. 3445 - 3448 (2007/10/03)
Deuterated homo- and heterocyclic aromatic substrates bearing various functionalities were prepared by isotope exchange in supercritical deuterium oxide, with little or no formation of byproducts. Equilibration was attained rapidly (1-24 hrs), and deuterium exchange extended to alpha positions of alkyl homologs. Nitro- and haloarenes, thioethers, telluroethers, and some heterocyclic substrates were unstable.
