33278-46-5

Usage

Uses

Used in Pharmaceutical and Medicinal Applications:
4-Pyridinecarboxamidine is used as a precursor in the synthesis of heterocyclic compounds for its potential pharmaceutical and medicinal properties. It plays a crucial role in the development of potential anti-inflammatory and anti-cancer drugs.
Used in Anti-Inflammatory and Anti-Cancer Drug Development:
4-Pyridinecarboxamidine is used as a key component in the formulation of drugs targeting inflammation and cancer. Its unique chemical structure allows it to modulate biological pathways involved in these conditions, offering a promising avenue for therapeutic intervention.
Used in Diabetes Treatment:
In the medical field, 4-Pyridinecarboxamidine is used as a component in treatments for diabetes, potentially aiding in the management of blood sugar levels and related metabolic issues.
Used in Alzheimer's Disease Management:
4-PYRIDINECARBOXAMIDINE is also being studied for its potential role in the treatment of Alzheimer's disease, where it may contribute to the modulation of neurodegenerative processes.
Used in Antimicrobial Research:
4-Pyridinecarboxamidine has been studied for its potential to inhibit the growth of certain bacteria and parasites, making it a valuable candidate in the field of antimicrobial research and drug development for new antibiotics and antiparasitic agents.

InChI:InChI=1/C6H7N3.C2H4O2/c7-6(8)5-1-3-9-4-2-5;1-2(3)4/h1-4H,(H3,7,8);1H3,(H,3,4)

Upstream product

• 378766-70-2 N'-(4-nitrophenylsulfonyloxy)isonicotinimidamide 
• 1612796-82-3 N'-(propylsulfonyloxy)isonicotinimidamide 

Downstream Products

• 141424-90-0 4,5-Bis-(4-methoxy-phenyl)-2-pyridin-4-yl-pyrimidine 
• 56406-44-1 4-oxo-2-pyridin-4-yl-3,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 259807-46-0 ethyl 2-(4-pyridyl)-5-pyrimidinecarboxylate 
• 204394-76-3 2-(pyridin-4-yl)pyrimidine-4,6-diol 
• 950486-10-9 C₂₀H₁₇N₅O₂S 
• 950486-01-8 C₂₀H₁₇N₅OS 
• 950486-03-0 C₁₈H₁₄N₆OS 
• 950485-83-3 C₁₉H₁₅N₅OS 
• 2208-59-5 2-(pyridin-4-yl)-1H-benzo[d]imidazole 
• 1426140-16-0 C₂₀H₁₃Cl₂N₅S 
• 1426140-23-9 1-phenyl-6-(phenylamino)-4-(pyridin-4-yl)-1,3,5-triazine-2(1H)-thione 
• 1426140-28-4 6-(p-tolylamino)-4-(pyridin-4-yl)-1-p-tolyl-1,3,5-triazine-2(1H)-thione 
• 1426140-32-0 6-(m-tolylamino)-4-(pyridin-4-yl)-1-m-tolyl-1,3,5-triazine-2(1H)-thione 
• 1438287-61-6 4-benzyl-4-phenyl-2-(pyridin-4-yl)-4H-imidazol-5-ol 

Relevant academic research and scientific papers

Evaluation of O-alkyl and aryl sulfonyl aromatic and heteroaromatic amidoximes as novel potent DNA photo-cleavers

Several stable O-alkyl and aryl sulfonyl conjugated p-nitro-Ph and o-, m-, p-pyridine N′-hydroxy imidamides, were subjected to UV irradiation at 312 nm with supercoiled circular plasmid DNA pBluescript KS II. The generated amidinyl and sulfonyloxyl radicals led to effective DNA photo-cleavage. Both alkyl and aryl sulfonyl derivatives were active and the order p-pyridine > p-nitro-Ph > o-pyridine > m-pyridine was schematized for the N′-hydroxy imidamides moiety. Calf thymus-DNA affinity studies which comprised UV interactions, viscosity experiments and competitive studies with ethidium bromide showed good to excellent affinity of the compounds. These properties revealed sulfonyl amidoximes as novel effective DNA-photo-cleavers and may serve in the discovery of new leads for "on demand" biotechnological and medical applications.