332865-87-9

Upstream product

• 84666-31-9 <(1E)-3-(benzyloxy)-1-propen-1-yl>tributylstannate 
• 4039-82-1 Benzyl propargyl ether 
• 332865-86-8 C₁₀⁽¹³⁾CH₁₀O₂ 

Relevant academic research and scientific papers

Regioselective synthesis of 13C1-labeled 2-deoxyribonolactones

Syntheses of the five regioselectively 13C1-labeled 5-O-benzyl-2-deoxyribonolactones are described. 13C1-Labeled deoxyribonolactones were prepared by addition of KCN to epoxides 7 and subsequent lactonization of the resulting nitriles. Integration of the independent schemes leading to the five isotopomers of 9 results in an efficient and cost effective preparation of labeled mixtures of 13C mono-labeled deoxyribonolactones. These mixtures are the pivotal intermediates in the preparation of 'population labeled' 13C-labeled nucleoside phosphoramidites for solid-phase oligonucleotide synthesis.