332886-16-5

Basic information

• Product Name: 4-(N-Methyl-N-phenylsulfamoyl)acetanilide, 97%
• Synonyms: 4-(N-Methyl-N-phenylsulfamoyl)acetanilide, 97%;Acetamide, N-[4-[(methylphenylamino)sulfonyl]phenyl]-;N-(4-{[methyl(phenyl)amino]sulfonyl}phenyl)acetamide;N-{4-[methyl(phenyl)sulfamoyl]phenyl}acetamide
• CAS NO: 332886-16-5
• Molecular Formula: C15H16N2O3S
• Molecular Weight: 304.36414
• Mol File: 332886-16-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(N-Methyl-N-phenylsulfamoyl)acetanilide, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N-Methyl-N-phenylsulfamoyl)acetanilide, 97%(332886-16-5)
• EPA Substance Registry System: 4-(N-Methyl-N-phenylsulfamoyl)acetanilide, 97%(332886-16-5)

Safety Data

• Hazardous Substances Data: 332886-16-5(Hazardous Substances Data)

Upstream product

• 100-61-8 N-methylaniline 
• 121-60-8 p-acetylaminobenzenesulfonyl chloride 
• 110-86-1 pyridine 
• 121-69-7 N,N-dimethyl-aniline 

Relevant articles and documents

Nanosized CdS as a Reusable Photocatalyst: The Study of Different Reaction Pathways between Tertiary Amines and Aryl Sulfonyl Chlorides through Visible-Light-Induced N-Dealkylation and C-H Activation Processes

It has been found that the final products of the reaction of sulfonyl chlorides and tertiary amines in the presence of cadmium sulfide nanoparticles under visible light irradiation are highly dependent on the applied reaction conditions. Interestingly, with the change of a reaction condition, different pathways were conducted (visible-light-induced N-dealkylation or sp3 and sp2 C-H activation) that lead to different products such as secondary amines and various sulfonyl compounds. Remarkably, all of these reactions were performed under visible light irradiation and an air atmosphere without any additive or oxidant in benign solvents or under solvent-free conditions. During this study, the CdS nanoparticles as affordable, heterogeneous, and recyclable photocatalysts were designed, successfully synthesized, and fully characterized and applied for these protocols. During these studies, intermediates resulting from the oxidation of tertiary amines are trapped during the photoinduced electron transfer (PET) process. The reaction was carried out efficiently with a variety of substrates to give the corresponding products at relatively short times in good to excellent yields in parallel with the use of the visible light irradiation as a renewable energy source. Most of these processes are novel or are superior in terms of cost-effectiveness, safety, and simplicity to published reports.

METHODS OF INHIBITING BACTERIAL VIRULENCE AND COMPOUNDS RELATING THERETO

The present invention relates to compounds and methods for the treatment of bacterial infections. Because their mechanism of action does not involve killing of bacteria or inhibiting their growth, the potential for these compounds to induce drug resistance in bacteria is minimized. Through inhibiting bacterial virulence, the present invention provides a novel means of treating bacterial infections.