332899-55-5 Usage
Explanation
The compound has a total of 12 carbon atoms, 14 hydrogen atoms, 2 nitrogen atoms, and 1 oxygen atom in its molecular structure.
2. Derivative of benzimidazole
Explanation
1H-Benzimidazole-2-methanol,1-propyl-(9CI) is derived from the benzimidazole structure, which is a heterocyclic aromatic organic compound.
3. Propyl group attachment
Explanation
A propyl group (C3H7) is attached to the 1-position of the benzimidazole ring, which influences the compound's chemical properties and reactivity.
4. Potential applications in pharmaceutical and chemical industries
Explanation
Due to its unique structure and properties, 1H-Benzimidazole-2-methanol,1-propyl-(9CI) may be used in the development of new drugs or other chemical products.
5. Building block for synthesis of other organic compounds
Explanation
The compound can serve as an intermediate or starting material in the synthesis of more complex organic molecules, making it a valuable component in organic chemistry.
6. Subject of interest for researchers and scientists
Explanation
The properties and potential uses of 1H-Benzimidazole-2-methanol,1-propyl-(9CI) make it an important subject for further study in various scientific fields, including chemistry, biology, and medicine.
7. Need for further research and testing
Explanation
To fully understand the potential applications and properties of 1H-Benzimidazole-2-methanol,1-propyl-(9CI), additional research and testing may be necessary to explore its capabilities and limitations.
Check Digit Verification of cas no
The CAS Registry Mumber 332899-55-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,2,8,9 and 9 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 332899-55:
(8*3)+(7*3)+(6*2)+(5*8)+(4*9)+(3*9)+(2*5)+(1*5)=175
175 % 10 = 5
So 332899-55-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2O/c1-2-7-13-10-6-4-3-5-9(10)12-11(13)8-14/h3-6,14H,2,7-8H2,1H3
332899-55-5Relevant academic research and scientific papers
Structure-Activity Relationship and Pharmacokinetic Studies of 1,5-Diheteroarylpenta-1,4-dien-3-ones: A Class of Promising Curcumin-Based Anticancer Agents
Wang, Rubing,Chen, Chengsheng,Zhang, Xiaojie,Zhang, Changde,Zhong, Qiu,Chen, Guanglin,Zhang, Qiang,Zheng, Shilong,Wang, Guangdi,Chen, Qiao-Hong
, p. 4713 - 4726 (2015/06/25)
Forty-three 1,5-diheteroaryl-1,4-pentadien-3-ones were designed as potential curcumin mimics, structurally featuring a central five-carbon dienone linker and two identical nitrogen-containing aromatic rings. They were synthesized using a Horner-Wadsworth-Emmons reaction as the critical step and evaluated for their cytotoxicity and antiproliferative activities toward both androgen-insensitive and androgen-sensitive prostate cancer cell lines and an aggressive cervical cancer cell line. Most of the synthesized compounds showed distinctly better in vitro potency than curcumin in the four cancer cell lines. The structure-activity data acquired from the study validated (1E,4E)-1,5-dihereroaryl-1,4-pentadien-3-ones as an excellent scaffold for in-depth development for clinical treatment of prostate and cervical cancers. 1-Alkyl-1H-imidazol-2-yl, ortho pyridyl, 1-alkyl-1H-benzo[d]imidazole-2-yl, 4-bromo-1-methyl-1H-pyrazol-3-yl, thiazol-2-yl, and 2-methyl-4-(trifluoromethyl)thiazol-5-yl were identified as optimal heteroaromatic rings for the promising in vitro potency. (1E,4E)-1,5-Bis(2-methyl-4-(trifluoromethyl)thiazol-5-yl)penta-1,4-dien-3-one, featuring thiazole rings and trifluoromethyl groups, was established as the optimal lead compound because of its good in vitro potency and attractive in vivo pharmacokinetic profiles. (Chemical Equation Presented).
