33313-80-3Relevant academic research and scientific papers
Reactivity pattern of bis(propargyloxy) disulfides: Tandem rearrangements and cyclizations
Braverman, Samuel,Pechenick-Azizi, Tatiana,Gottlieb, Hugo E.,Sprecher, Milon
experimental part, p. 1741 - 1750 (2011/07/09)
Thirty-five substituted bis(propargyloxy) disulfides were successfully prepared in good to excellent yields, and their reactivity was found to be strongly dependent on the substitution pattern of the reactant. Inter alia they undergo surprising tandem sigmatropic rearrangements and cycloadditions. Three heretofore unknown product types were isolated and fully characterized: 6,7-dithiabicyclo[3.1.1]heptan-2-one 6-oxide derivatives, two isomeric 1,2-dithiete 1,1-dioxides (α,β-unsaturated four-membered cyclic thiosulfonates) from bis(propargyloxy) disulfides with α- or γ-alkyl-substituted propargyl groups, and two isomeric 2-oxa-5,7-dithiabicyclo[2.2.1]heptane 5-oxides from bis(propargyloxy) disulfides with α-tert-butyl- or α,α-dialkyl-substituted propargyl groups. Georg Thieme Verlag Stuttgart - New York.
A Novel Synthesis of Allenic Lactones by Use of the Sigmatropic Rearrangement of Cyclic Propargylsulfonium Ylides
Kido, Fusao,Abiko, Toshiya,Kato, Michiharu
, p. 2471 - 2474 (2007/10/02)
The sigmatropic rearrangement of the cyclic propargylsulfonium ylides generated from ethyl 5-phenylthio-3-pentynyl and ethyl 6-phenylthio-4-hexynyl diazomalonates provided the novel allenic lactones, 2-ethoxycarbonyl-2-phenylthio-3-vinylidene-5-penta
16-Substituted polyunsaturated hexadecanoic fatty acids
-
, (2008/06/13)
Sixteen carbon atom carboxylic acids having 16-phenoxy or 16-phenylthio substituents, and 0, 1, or 4 triple bonds, methods of preparing them, and pharmaceutical preparations containing them. These compounds are useful as lipoxygenase inhibitors.
