333327-12-1

Basic information

• Product Name: 2,3,4-tri-O-(methoxymethyl)-5a-carba-β-L-arabino-hex-5-enopyranosyl bromide
• Synonyms: 2,3,4-tri-O-(methoxymethyl)-5a-carba-β-L-arabino-hex-5-enopyranosyl bromide
• CAS NO: 333327-12-1
• Molecular Weight: 355.226
• Mol File: 333327-12-1.mol

Chemical Properties

• CAS DataBase Reference: 2,3,4-tri-O-(methoxymethyl)-5a-carba-β-L-arabino-hex-5-enopyranosyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-tri-O-(methoxymethyl)-5a-carba-β-L-arabino-hex-5-enopyranosyl bromide(333327-12-1)
• EPA Substance Registry System: 2,3,4-tri-O-(methoxymethyl)-5a-carba-β-L-arabino-hex-5-enopyranosyl bromide(333327-12-1)

Safety Data

• Hazardous Substances Data: 333327-12-1(Hazardous Substances Data)

Upstream product

• 305819-68-5 2,3,4-tri-O-acetyl-6-bromo-6-deoxy-5a-carba-β-L-glucopyranosyl bromide 
• 333327-06-3 2,3-di-O-acetyl-4-O-mesyl-5a-carba-β-L-hex-5-enopyranosyl bromide 
• 305819-70-9 2,3,4-tri-O-acetyl-5a-carba-β-L-xylo-hex-5-enopyranosyl bromide 
• 305819-72-1 2,3,4-tri-O-acetyl-5a-carba-β-L-arabino-hex-5-enopyranosyl bromide 
• 305369-74-8 Methanesulfonic acid (3aS,4S,7S,7aS)-7-bromo-2,2-dimethyl-5-methylene-hexahydro-benzo[1,3]dioxol-4-yl ester 
• 305369-73-7 2,3-O-isopropylidene-5a-carba-β-L-xylo-hex-5-enopyranosyl bromide 
• 1054643-34-3 5a-carba-β-L-xylo-hex-5-enopyranosyl bromide 

Downstream Products

• 333327-23-4 (1R,2R,3R,4S,6R)-4-(methanesulfonyloxymethyl)-1,2,3-tri-O-(methoxymethyl)-6-methyl-1,2,3-cyclohexanetriol 
• 333327-33-6 (1S,2S,3R,4R,5R)-1-(azidomethyl)-2,3,4-tri-O-(methoxymethyl)-5-methyl-1,2,3,4-cyclohexanetetrol 
• 333327-32-5 (1R,2S,3R,4R,5R)-1-(azidomethyl)-2,3,4-tri-O-(methoxymethyl)-5-methyl-1,2,3,4-cyclohexanetetrol 
• 305369-77-1 2,3,4-tri-O-(methoxymethyl)-5a-carba-α-L-fucopyranosyl acetate 
• 333327-21-2 2,3,4-tri-O-(methoxymethyl)-5a-carba-α-L-fucopyranosyl azide 
• 333327-28-9 (1R,2R,3R,4S,6R)-4-(hydroxymethyl)-1,2,3-tri-O-(methoxymethyl)-6-methyl-1,2,3-cyclohexanetriol 
• 333327-22-3 2,3,4-tri-O-(methoxymethyl)-5a-carba-β-L-fucopyranosylcarbonitrile 
• 333327-26-7 (1R,2R,3R,6R)-1,2,3-tri-O-(methoxymethyl)-6-methyl-4-methylene-1,2,3-cyclohexanetriol 
• 141436-56-8 1L-(1,2,3/4,5)-1-C-Methyl-2,3,4,5-cyclohexanetetrol 
• 305369-76-0 2,3,4-tri-O-(methoxymethyl)-5a-carba-β-L-fucopyranosyl bromide 

Relevant articles and documents

Synthesis and biological evaluation of α-L-fucosidase inhibitors: 5a-carba-α-L-fucopyranosylamine and related compounds

5a-Carba-α-L-fucopyranosylamine (5), an α-glucosidase inhibitor validamine analog possessing an α-L-fucose-type structure, and four related compounds (4 and 6-8) were synthesized and their glycosidase inhibitory potential determined. Carbafucosylamine has already been shown to possess a specific and very strong inhibitory activity against α-L-fucosidase (Ki = 1.2 × 10-8 M, bovine kidney). Judging from the activity of the other analogs prepared, this amine might be expected to be a lead compound for development of a new type of α-L-fucosidase inhibitor.