333344-35-7

Upstream product

• 100-83-4 meta-hydroxybenzaldehyde 
• 109-77-3 malononitrile 
• 108-46-3 recorcinol 

Relevant academic research and scientific papers

Heterogenization of an imidazolium ionic liquid based on magnetic carbon nanotubes as a novel organocatalyst for the synthesis of 2-amino-chromenes via a microwave-assisted multicomponent strategy

Imidazolium ionic liquid functionalized magnetic multiwalled carbon nanotubes (CNTs-Fe3O4-IL) were synthesized and the structure, morphology and properties of nanocomposites were investigated using different characterization techniqu

Green protocol for synthesis of MgFe2O4 nanoparticles and study of their activity as an efficient catalyst for the synthesis of chromene and pyran derivatives under ultrasound irradiation

In this study, the MgFe2O4 nanoparticles were synthesized via a green and simple approach. Then an effective procedure to synthesize 2-amino-7-hydroxy-4H-chromene and tetrahydrobenzo[b]pyran derivatives was established through the ch

Prolinamide functionalized polyacrylonitrile fiber with tunable linker length and surface microenvironment as efficient catalyst for Knoevenagel condensation and related multicomponent tandem reactions

A series of new prolinamide polyacrylonitrile fiber catalysts with tunable length of alkyl linker and different linker group were prepared by covalent bonding for the first time and well characterized by mechanical strength, FT-IR, XRD, EA, TGA, SEM and water contact angel. The catalytic activities of these fiber catalysts were evaluated in Knoevenagel condensation and one-pot Knoevenagel-Michael multicomponent tandem reactions to synthesize α, β-unsaturated nitrile and 2-amino-4H-chromene derivatives in water. The result show that the suitable linker length attaching amines to fiber matrix as well as the constructed hydrophobic microenvironment by linker group within the surface layers of fiber materials effectively promotes the reactions. In addition, the good swollen capacity of fiber in solvent ensure that the reaction proceed well. Fiber catalyst PANPA?2F modified by prolinamide with a C2 alkyl chain exhibited the best catalytic performance and can be easily recovered and reused for at least ten consecutive cycles without significant loss of catalytic activity and active sites leaching.

Enhancement of catalytic activity in the synthesis of 2-amino-4H-chromene derivatives using both copper- and cobalt-incorporated magnetic ferrite nanoparticles

Cu0.5Co0.5Fe2O4 magnetic nanoparticles were prepared, characterized and employed as bench-top, highly active and magnetically separable nanocatalysts for the synthesis of 2-amino-4H-chromene derivatives. A wide

The amino side chains do matter: Chemoselectivity in the one-pot three-component synthesis of 2-amino-4: H -chromenes by supramolecular catalysis with amino-appended β-cyclodextrins (ACDs) in water

In this study, the one-pot three-component synthesis of 2-amino-4H-chromenes was accomplished by supramolecular catalysis using a series of well-designed amino-appended β-cyclodextrins (ACDs) in water. The catalytic mechanism was elucidated in detail with 1D and 2D NMR and ESI-MS analyses, while the key roles of amino side chains of ACDs in the reaction chemoselectivity were addressed for the first time.

A 4H - 4 - benzenes chromenes preparation method

The invention discloses a 4H-4-arylbenzopyran compound preparation method. According to the method, triethylenetetramine-beta-cyclodextrin is adopted as a catalyst; aromatic aldehyde, malononitrile and resorcinol are adopted as raw materials; water is ado

Application of {[4,4′-BPyH][C(CN)3]2} as a Bifunctional Nanostructured Molten Salt Catalyst for the Preparation of 2-Amino-4 H -chromene Derivatives under Solvent-Free and Benign Conditions

The bifunctional nanostructured molten salt [4,4′-bipyridine]-1,1′-diium tricyanomethanide has been employed as a highly efficient and powerful catalyst for the preparation of 2-amino-4H-chromenes. A wide variety of aromatic aldehydes was condensed with m

An efficient, one-pot synthesis of 2-amino-4H-chromenes catalyzed by (α-Fe2O3)-MCM-41-supported dual acidic ionic liquid as a novel and recyclable magnetic nanocatalyst

A novel (α-Fe2O3)-MCM-41-supported dual acidic ionic liquid (DAIL) catalytic system was prepared. This catalyst was characterized by XRD, TEM, SEM, IR spectra and N2 adsorption-desorption measurements, TGA and acid-base titration. 1-Methyl-3-(4-sulfobutyl) imidazolium hydrogen sulfate as the DAIL inside the mesochannels of α-Fe2O3-MCM-41 led to preparation of a new material which was an efficient magnetic heterogeneous nanocatalyst for one-pot three-component synthesis of some new and known 2-amino-4H-chromenes in water medium conditions. This catalyst was more efficient than other reported catalysts for the synthesis of 2-amino-3-cyano-7-hydroxy-4H-chromenes. High product yields, short reaction times, use of non-corrosives, a robust and reusable magnetic nanocatalyst and water as a green solvent are the most important features of the present work. Graphical Abstract: [Figure not available: see fulltext.]

Sulfonic acid-functionalized MIL-101(Cr) as a highly efficient heterogeneous catalyst for one-pot synthesis of 2-amino-4H-chromenes in aqueous medium

Sulfonic acid-functionalized MIL-101(Cr) was established to be an active heterogeneous catalyst for the one-pot synthesis of 2-amino-4H-chromenes via a three-component condensation reaction between resorcinol, malononitrile and a diverse range of aromatic

Ultrasound assisted the green synthesis of 2-amino-4H-chromene derivatives catalyzed by Fe3O4-functionalized nanoparticles with chitosan as a novel and reusable magnetic catalyst

Fe3O4 nanoparticles were prepared by chemical coprecipitation method. Subsequently immobilization of chitosan on Fe 3O4 nanoparticles was accomplished and afforded magnetic Fe3O4-chitosan nanoparticles. Synthesized nanoparticles was found to be a magnetic and heterogeneous catalyst for a one-pot and efficient synthesis of 2-amino-4H-chromenes by condensation of aldehydes with malononitrile and resorcinol under ultrasound irradiation as an ecofriendly method. This convenient procedure allowed us to achieve products under ultrasound irradiation in short time and excellent yield without using of harmful catalyst. The present method will permit a further increase of the diversity within the 2-amino-4H-chromene family.