333347-47-0Relevant academic research and scientific papers
Direct and Selective C-H Carbamoylation of (Hetero)aromatics with TMSOTf-Activated Carbamoyl Chloride
Uehara, Ayaka,Olivero, Sandra,Michelet, Bastien,Martin-Mingot, Agnès,Thibaudeau, Sébastien,Du?ach, Elisabet
, p. 46 - 49 (2019)
Exploiting trimethylsilyltrifluoromethanesulfonate as Lewis acid, (hetero)aromatics underwent regioselective and direct carbamoylation. The method is based on the in situ generation of a highly electrophilic carbamoyl triflate active species.
