333354-35-1

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 119336-08-2 methyl (R)-2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3-iodophenyl)propanoate 

Downstream Products

• 333354-24-8 (2S,4S,6R,7S,9S)-9-[(R)-2-[(2-tert-Butoxycarbonylamino-acetyl)-methyl-amino]-3-(3-iodo-4-triisopropylsilanyloxy-phenyl)-propionyloxy]-7-(tert-butyl-dimethyl-silanyloxy)-2,4,6,10-tetramethyl-undecanoic acid tert-butyl ester 
• 333354-26-0 Trifluoro-acetic acid (3R,9S,11S,13R,14S,16S)-3-(3-iodo-4-triisopropylsilanyloxy-benzyl)-16-isopropyl-4,9,11,13-tetramethyl-2,5,8-trioxo-1-oxa-4,7-diaza-cyclohexadec-14-yl ester 
• 333354-25-9 (3R,9S,11S,13R,14S,16S)-14-Hydroxy-3-(3-iodo-4-triisopropylsilanyloxy-benzyl)-16-isopropyl-4,9,11,13-tetramethyl-1-oxa-4,7-diaza-cyclohexadecane-2,5,8-trione 
• 333354-37-3 (R)-2-[(2-tert-Butoxycarbonylamino-acetyl)-methyl-amino]-3-(3-iodo-4-triisopropylsilanyloxy-phenyl)-propionic acid 
• 333354-23-7 (R)-2-[(2-tert-Butoxycarbonylamino-acetyl)-methyl-amino]-3-(3-iodo-4-triisopropylsilanyloxy-phenyl)-propionic acid methyl ester 
• 333354-36-2 (R)-3-(3-Iodo-4-triisopropylsilanyloxy-phenyl)-2-methylamino-propionic acid methyl ester 
• 156953-84-3 (3R,9S,11S,13R,14S,16S)-14-hydroxy-3-[(4-hydroxy-3-iodophenyl)methyl]-4,9,11,13-tetramethyl-16-(propan-2-yl)-1-oxa-4,7-diazacyclohexadecane-2,5,8-trione 
• 333354-22-6 2-(tert-butoxycarbonyl-methyl-amino)-3-(3-iodo-4-triisopropylsilanyloxy-phenyl)-propionic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of antitumor depsipeptide (-)-doliculide.

[reaction: see text] (-)-Doliculide, a potent antitumor agent, is synthesized stereoselectively in a convergent manner. The key strategy involves a stereoselective synthesis of the polyketide unit and synthesis of the D-tyrosine derivative, followed by as