333361-07-2Relevant academic research and scientific papers
Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2
Ellsworth, Bruce A.,Meng, Wei,Patel, Manorama,Girotra, Ravindar N.,Wu, Gang,Sher, Philip M.,Hagan, Deborah L.,Obermeier, Mary T.,Humphreys, William G.,Robertson, James G.,Wang, Aiying,Han, Songping,Waldron, Thomas L.,Morgan, Nathan N.,Whaley, Jean M.,Washburn, William N.
scheme or table, p. 4770 - 4773 (2009/05/07)
Inhibition of sodium-dependent glucose transporter 2 (SGLT2), the transporter that is responsible for renal re-uptake of glucose, leads to glucosuria in animals. SGLT-mediated glucosuria provides a mechanism to shed excess plasma glucose to ameliorate dia
