33341-63-8Relevant academic research and scientific papers
Direct access to cobaltacycles via C-H activation: N-chloroamide- enabled room-temperature synthesis of heterocycles
Yu, Xiaolong,Chen, Kehao,Guo, Shan,Shi, Pengfei,Song, Chao,Zhu, Jin
supporting information, p. 5348 - 5351 (2017/11/07)
Cobaltacycle synthesis via C-H activation has been achieved for the first time, providing key mechanistic insight into cobalt catalytic chemistry. NChloroamides are used as a directing synthon for cobalt-catalyzed roomtemperature C-H activation and construction of heterocycles. Alkynes as coupling partners allow convenient access to isoquinolones, a class of synthetically and pharmaceutically important compounds. The broad substrate scope enables a diverse range of substitution patterns to be incorporated into the heterocyclic scaffold.
13C Nuclear Magnetic Resonance Study of ?-Polarization in 3- and 4-Substituted Benzamides and N-Chlorobenzamides
Rosa, Michael De,Brown, Keith,McCoy, Mary,Ong, Kevin,Sanford, Kimberley
, p. 1787 - 1790 (2007/10/02)
The substituent effect on the carbonyl carbon 13C chemical shift in 3- and 4-substituted benzamides and N-chlorobenzamides has been studied in (CD3)2SO.Chlorine shields the carbonyl carbon.A cross correlation was carried out for C(α) and the carbon
