333459-71-5

Usage

Uses

Used in Pharmaceutical Synthesis:
2-Amino-6-chloro-3-nitrobenzonitrile is used as a key intermediate in the synthesis of pharmaceuticals for its versatile reactivity and functional groups. It aids in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 2-Amino-6-chloro-3-nitrobenzonitrile is utilized as a starting material for the production of various agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Dye Manufacturing:
2-Amino-6-chloro-3-nitrobenzonitrile is employed as a chemical intermediate in the manufacturing of dyes, where its unique properties allow for the creation of a wide range of colorants for various applications.
Used in Organic Intermediates:
2-aMino-6-chloro-3-nitrobenzonitrile is also used in the production of various organic intermediates, which are essential building blocks for the synthesis of other complex organic compounds in the chemical industry.
Safety Note:
2-Amino-6-chloro-3-nitrobenzonitrile is considered to be a hazardous chemical and should be handled with care due to its potential health and environmental risks. Proper safety measures and precautions should be taken during its use and disposal to minimize any adverse effects.

Upstream product

• 5866-98-8 2,6-dichloro-3-nitrobenzonitrile 

Downstream Products

• 333458-30-3 2-(3-amino-2-cyano-4-nitrophenyl)-2-methyl-3-oxobutyric acid ethyl ester 
• 500735-17-1 2-amino-3-nitro-6-(2-oxo-propyl)-benzonitrile 
• 548457-80-3 2,3-diamino-6-chlorobenzonitrile 
• 870486-61-6 3-amino-2'-methoxy-4-nitro-biphenyl-2-carbonitrile 
• 524695-75-8 2-(3,4-diamino-2-cyanophenyl)-2-methyl-3-oxobutyric acid ethyl ester 
• 333455-11-1 2-(2,6-Dichlorophenylamino)-6,7-dimethyl-1,8-dihydro-imidazo[4,5-h]isoquinoline-9-one 
• 500735-21-7 2-[4-cyano-2-(2,6-dichloro-phenylamino)-3H-benzoimidazol-5-yl]-2-methyl-3-oxo-butyric acid ethyl ester 
• 500735-25-1 2-(2,6-dichloro-phenylamino)-5-(2-oxo-propyl)-3H-benzoimidazole-4-carbonitrile 

Relevant academic research and scientific papers

Structure-based design and synthesis of benzimidazole derivatives as dipeptidyl peptidase IV inhibitors

A novel series of non-covalent, benzimidazole-based inhibitors of DPP-4 has been developed from a small fragment hit using structure-based drug design. A highly versatile synthetic route was created for the development of SAR, which led to the discovery o

NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

The invention provides a compound of Formula I (I) wherein n is 1 or 2; R1 is selected from hydrogen, halogen, CN, COOR6, CONR6R7 or CH2OR6; R2 is selected from hydrogen, halogen

Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: Orally active inhibitors of lck kinase

The tyrosine kinase p56lck (lck) is essential for T cell activation; thus, inhibitors of lck have potential utility as autoimmune agents. Our initial disclosure of a new class of lck inhibitors based on the phenylaminoimidazoisoquinolin-9-one showed reaso

Heterocyclic compounds useful as inhibitors of tyrosine kinases

Disclosed are novel compounds of formula (I): wherein Ar1, Ra, R4, R5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases asso

Isoquinolinone synthesis by SNAr reaction: A versatile route to imidazo[4,5-h]isoquinolin-9-ones

Reaction of 2-chlorobenzonitriles with β-ketoesters in an SNAr reaction, followed by cyclization in acid provides a versatile route to isoquinolones. Starting from 2,6-dichloro-3-nitrobenzonitrile 7, sequential displacement of the chlorines by

Heterocyclic compounds useful as inhibitors of tyrosine kinases

Disclosed are novel compounds of formula (I): wherein Ar1, Ra, R4, R5, X and Y are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases asso