33354-98-2Relevant academic research and scientific papers
Dearomatization of N-phenyl-2,6-dialkylpiperidines: Practical synthesis of (±)-solenopsin A and (±)-dihydropinidine
Girard, Nicolas,Gautier, Cyrille,Malassene, Richard,Hurvois, Jean-Pierre,Moinet, Claude,Toupet, Loic
, p. 2005 - 2009 (2007/10/03)
The fire ant venom alkaloid (±)-solenopsin A was prepared in 4 steps (34%) starting from the N-phenyl-2-undecyl piperidine (1c). The key step in this synthesis involved the dearomatization of the phenyl group of N-phenyl-2-methyl-6-undecyl-piperidine (9c), which was carried out under Birch conditions.
