33367-55-4

Usage

Uses

Used in Flavoring and Fragrance Industry:
Diethyl 2,3-diisopropylsuccinate is utilized as a flavoring agent and fragrance ingredient in the food and cosmetic industries. Its fruity and floral scent, which resembles the aroma of apple and peach, makes it a valuable addition to enhance the sensory experience of various products.
Used in Solvent Applications:
DIIPS also serves as a solvent in certain applications, capitalizing on its chemical properties to dissolve or carry other substances effectively.
Used in Pharmaceutical and Organic Synthesis:
Due to its unique chemical structure, diethyl 2,3-diisopropylsuccinate may have potential uses in pharmaceuticals and organic synthesis. Its versatility in chemical reactions could contribute to the development of new compounds and medicines.
Used in Research and Development:
The relatively safe profile of DIIPS, based on current available data, makes it a candidate for further research and development in various industries, potentially leading to new applications and innovations.

Upstream product

• 15112-52-4 monoethyl ester of isopropylmalonic acid 
• 609-12-1 ethyl 2-bromoisovalerate 
• 18292-38-1 2-methallyltrimethylsilane 
• 63547-55-7 1-ethoxy-3-methyl-1-trimethylsiloxybut-1-ene 
• 64-17-5 ethanol 
• 91007-67-9 2,3-diisopropylsuccinic acid 
• 3213-49-8 ethyl 2-isopropylcyanoacetate 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 108-64-5 Ethyl isovalerate 

Downstream Products

• 91007-67-9 Meso-α,α'Diisopropyl-Bernsteinsaeure 
• 91007-67-9 (+/-)-2,3-Diisopropyl-bernsteinsaeure 

Relevant academic research and scientific papers

2,3-hydrocarbyl substituted succinic acid diester synthesis and use

The invention relates to synthesis and application of 2,3-hydrocarbyl substituted diester succinate. At a low temperature, carboxylic ester and strong base LDA (Lithium Diisopropylamide) react to form alkenyl alkoxide which is oxidized and coupled by carbon tetrachloride to prepare 2,3-hydrocarbyl substituted diester succinate. Liquid nitrogen has the gas protecting and refrigerating functions by a novel method of introducing liquid nitrogen to a reaction system to perform direct refrigeration. The direct refrigerating method has the advantages of energy conservation, easiness in control of reaction temperature, and replacement of inertial protective gas. The 2,3-hydrocarbyl substituted diester succinate can be used as an electron donor of a polypropylene catalyst.

PROCESS FOR PREPARING 2,3-DI-NON-STRAIGHT-ALKYL-2-CYANO SUCCINIC ACID DIESTERS

A process for preparing 2,3-di(non-linear-alkyl)-2-cyanosuccinate compounds, especially 2,3-diisopropyl-2-cyanosuccinate compounds, and processes for preparing 2.3-di(non-linear-alkyl)succinic acids and esters thereof by using the 2,3-di-non-linear propyl-2-cyanosuccinate compounds as intermediates are disclosed.

Synthesis of (arylimido)vanadium complexes and their application for oxidative coupling reactions of silyl enol ether derivatives

(Arylimido)vanadium(v) complexes, V(NAr)(OEt)Cl2 [Ar = C 6H5, p-BrC6H4, p-(MeO)C 6H4] or V(NAr)Cl3 [Ar = o-BrC6H 4, o-(MeO)C6H4] were synthesized by the reaction of VO(OEt)Cl2 or VOCl3, respectively, with the corresponding aryl isocyanates. X-Ray crystal structure determination for V(NAr)(OEt)Cl2 (Ar = C6H5 and p-BrC 6H4) elucidates the alkoxido-bridged dimeric building blocks [V(NAr)(OEt)Cl2]2, wherein the substituent on the benzene ring was found to affect the character of the imido nitrogen. The 51V NMR spectroscopic measurements indicated that the electronic state of the vanadium metal centre depends on the ligands connecting to the vanadium and the substituents on the benzene ring. The selective oxidative cross-coupling reaction of silyl ketene acetal with silyl enol ether was achieved using V(Np-BrC6H4)Cl3 or V(No-BrC 6H4)Cl3.

Versatile Desilylative Cross-Coupling of Silyl Enol Ethers and Allylic Silanes via Oxovanadium-Induced Chemoselective One-Electron Oxidation

The chemoselective cross-coupling of silyl enol ethers and allylic silanes to γ,δ-unsaturated ketones is achieved by the oxovanadium(V)-induced oxidative desilylation of the more readily oxidizable organosilicon compounds.

Oxidative Dimerization of Lithium-Enolates of Esters Promoted by Titanium Tetrachloride

Oxidative dimerization of lithium ester enolates is effectively promoted by TiCl4, which serves as a new and efficient synthetic method.Mechanistic study indicates that the reaction proceeds via a radical-like mechanism, but it is not a free radical process.