3337-86-8

Usage

InChI:InChI=1/C8H6N2S/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)/p-1

Upstream product

• 2454-39-9 2-aminobenzothioamide 
• 84671-74-9 4-<3-(4-oxoquinazolinyl)>propiophenone 
• 84671-73-8 4-(4-quinazolinylthio)butan-2-one 

Downstream Products

• 95616-37-8 S-(4-quinazolinyl)-α-phenylthioglycolic acid 
• 91859-59-5 Anhydro-3-hydroxy-2-phenylthiazolo<3,2-c>quinazolin-4-ium hydroxyide 
• 77143-96-5 4-<(α-Hydroxycyclohexyl)thio>quinazoline 
• 84671-74-9 4-<3-(4-oxoquinazolinyl)>propiophenone 
• 106657-33-4 α-(4-quinazolinylthio)butyrophenone 
• 77143-94-3 4-<(α-Cyclohexenyl)thio>quinazoline 
• 491-36-1 4-Hydroxyquinazoline 
• 1429045-85-1 C₂₂H₁₆N₆S 
• 1429045-86-2 C₂₂H₁₆N₆S 
• 102244-04-2 4-(5-Nitro-quinolin-8-ylsulfanyl)-quinazoline 
• 118272-55-2 4-(pyridin-2-ylmethylthio)-quinazoline 
• 6956-67-8 4-benzylthioquinazoline 
• 6956-69-0 4-(2-Furylmethylthio)-quinazoline 

Relevant academic research and scientific papers

EXTRUSION REACTIONS-VI. TRANSFORMATIONS OF BETA(4-QUINAZOLINYLTHIO)KETONES TO 3-(BETA KETOALKYL)-4(3H)-QUINAZOLONE DERIVATIVES

4-(4-Quinazolinylthio)-butan-2-one and 3-(4-quinazolinylthio) propiophenone (4, R=CH3, C6H5) with POCl3 give 3-(3-oxobutyl)-4(3H)-quinazolone and 3-(2-benzoylethyl)-4(3H)-quinazolone (7, R=CH3, C6H5, X=O) via S N rearrangement followed by =C=S to =C=O conversion.Non-protic heterocyclic thioamides undergo similar oxidation.

A Novel Phosphorus Oxychloride Induced Conversion of β-(4-Quinazolinylthio) Ketones into β- Ketones

β-(4-Quinazolinylthio)ketones have been converted into β- ketones on refluxing their solutions in phosphorus oxychloride.

Reaction of 2-Aminobenzamide Analogs and 2-Aminothiophenol with Ethyl 3-Ethoxymethylene-2,4-dioxovalerate. Synthesis of Pyrroloquinazoline and Pyrrolobenzothiazoline Derivatives

The reaction of ethyl 3-ethoxymethylene-2,4-dioxovalerate (EMDV) (1) with 2-aminobenzamide (2), 2-aminobenzthioamide (3), 2-aminobenzmethylamide (4) and 3-amino-2-methyl- or phenylpyrazole-4-carboxamides (6 and 7) produced ethyl 3-aminomethylene-2,4-dioxovalerates (10, 15, 16, 18 and 19), which led to pyrroloquinazoline-1,5-diones (11, 22 and 23) and pyrrolopyrazolopyrimidine-1,5-diones (24 and 25) under the acidic condition, respectively.Analogously, 2-aminothiophenol reacted with 1 to give 21, which was subsequently derived to pyrrolobenzothiazolin-1-one (26) under the neutral condition.Furthermore, we prepared the heterocyclic steroidal molecules (41, 43, 45, 47, 49 and 51) by condensation of 11 and 26 with hydrazine, methylhydrazine and phenylhydrazine.