333724-35-9Relevant academic research and scientific papers
Synthesis of the A-B subunit of angelmicin B
Lambert, William T.,Roush, William R.
, p. 5501 - 5504 (2007/10/03)
(Chemical Equation Presented) An efficient synthesis of the tricyclic A-B subunit 2 of angelmicin B is described. A formal three-component coupling of aldehydes 4 and 6 with γ-silylallylborane 7 was employed to assemble the tetrahydrofuranyl core of 2, a strategy highlighted by the stereoselective [3 + 2] annulation of allylsilanes 5a/5b with aldehyde 4. The efficiency of the [3 + 2] annulation was greatly improved by using the allylic benzhydryldimethylsilane 5b compared to the allylic phenyldimethylsilane 5a.
Stereoselective synthesis of substituted γ-butyrolactones by the [3 + 2] annulation of allylic silanes with chlorosulfonyl isocyanate: Enantioselective total synthesis of (+)-blastmycinone
Peng, Zhi-Hui,Woerpel
, p. 675 - 678 (2007/10/03)
Equation presented (+)-blastmycinone A stereoselective synthesis of γ-butyrolactones by the [3 + 2] annulation of allylic silanes with N-chlorosulfonyl isocyanate (CSI) was developed. An enantioselective total synthesis of (+)-blastmycinone was accomplish
