333748-88-2 Usage
Chemical structure
2-(2,4-Dichloro-phenyl)-N-hydroxy-acetamidine is a compound consisting of a phenyl ring with two chlorine atoms (Cl) at the 2 and 4 positions, and a hydroxy-acetamidine group (NHOCH2CONH2) attached to the phenyl ring.
Potential applications
2-(2,4-DICHLORO-PHENYL)-N-HYDROXY-ACETAMIDINE has the potential for use in medicinal chemistry, including as a pharmaceutical intermediate, which can be further modified to create drugs and biologically active molecules.
Hydrogen bonding
The presence of the hydroxyl group (-OH) in the compound allows for the possibility of hydrogen bonding, which can influence the compound's solubility, stability, and interactions with other molecules.
Electron-withdrawing chloro substituents
The two chlorine atoms attached to the phenyl ring act as electron-withdrawing groups, which can affect the compound's reactivity, stability, and potential applications in various chemical and pharmaceutical processes.
Further research and development
To fully understand and harness the potential applications of 2-(2,4-Dichloro-phenyl)-N-hydroxy-acetamidine, additional research and development are needed to explore its properties, reactivity, and potential uses in the creation of new drugs and biologically active molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 333748-88-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,3,7,4 and 8 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 333748-88:
(8*3)+(7*3)+(6*3)+(5*7)+(4*4)+(3*8)+(2*8)+(1*8)=162
162 % 10 = 2
So 333748-88-2 is a valid CAS Registry Number.
333748-88-2Relevant academic research and scientific papers
Discovery of potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70
Vu, Chi B.,Corpuz, Evelyn G.,Merry, Taylor J.,Pradeepan, Selvaluxmi G.,Bartlett, Catherine,Bohacek, Regine S.,Botfield, Martyn C.,Eyermann, Charles J.,Lynch, Berkley A.,MacNeil, Ian A.,Ram, Mary K.,Van Schravendijk, Marie Rose,Violette, Shelia,Sawyer, Tomi K.
, p. 4088 - 4098 (2007/10/03)
A series of 1,2,4-oxadiazole analogues has been shown to be potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70, a potential therapeutic target for immune suppression. These compounds typically are 200- 400-fold more potent than the native,
