333749-07-8

Upstream product

• 54125-02-9 danishefsky's diene 
• 135-02-4 ortho-anisaldehyde 
• 71735-01-8 (E)-3-(tert-butyldimethylsilyloxy)-1-methoxy-1,3-butadiene 

Relevant academic research and scientific papers

Stereoselective hetero Diels-Alder reactions of chiral tricarbonyl (η6-benzaldehyde)chromium complexes

The ZnCl2-promoted cycloaddition of a series of enantiopure ortho -substituted benzaldehyde-Cr(CO)3 complexes and Danishefsky's diene gave the corresponding 2-aryl pyranones in good yields and complete enantiospecificity. Some of the

Chiral Chromium Salen@rGO as Multipurpose and Recyclable Heterogeneous Catalyst

The first immobilization of a pyrene-tagged chromium salen complex through π-π noncovalent interactions on reduced graphene oxide (rGO) is described. A very robust supported catalytic system is obtained to promote asymmetric catalysis in repeated cycles, without loss of activity or enantioselectivity. This specific behavior was demonstrated in two different catalytic reactions (up to ten reuses) promoted by chromium salen complexes, the cyclohexene oxide ring-opening reaction and the hetero-Diels-Alder cycloaddition between various aldehydes and Danishefsky's diene. Furthermore, the chiral chromium salen@rGO has been found to be compatible with a multi-substrate type use, in which the structure of the substrate involved is modified each time the catalyst is reused.

Discovery of exceptionally efficient catalysts for solvent-free enantioselective hetero-Diels-Alder reaction

Combinatorial coordination chemistry strategy combined with high-throughput screening techniques has been successfully applied to engineering practical enantioselective catalysts for asymmetric hetero-Diels-Alder reaction. The reaction of Danishefsky's di

A highly enantioselective hetero-Diels-Alder reaction of aldehydes with Danishefsky's diene catalyzed by chiral titanium(IV) 5,5′,6,6′,7,7′,8,8′-octahydro-1,1′ -bi-2-naphthol complexes

The catalytic effect of chiral Lewis acids on the hetero-Diels-Alder reaction between aldehydes and Danishefsky's diene (1) has been investigated. A variety of combinations of different ligands and Lewis acids have been examined as catalysts for the heter

Lewis acid catalysis of second-generation metallosalen complexes: An explanation for stereochemistry of asymmetric hetero Diels-Alder reaction

Chloro nitrosyl (R,S)-(salen)ruthenium(II) complex served as a good catalyst for asymmetric hetero Diels-Alder (HDA) reaction of Danishefsky's diene with a wide variety of aldehydes. In contrast with this, (R,R)-(salen)-chromium(III) and -manganese(III) c

Highly active 3-oxobutylideneaminatocobalt complex catalysts for an enantioselective hetero Diels-Alder reaction

Optically active 3-oxobutylideneaminatocobalt(III) complexes were developed as effective catalysts for the enantioselective hetero Diels-Alder reaction of aromatic and aliphatic aldehydes with 3-(t-butyldimethylsilyloxy)-1-methoxy-1,3-butadiene. In the presence of the highly active cationic cobalt(III) complex, the hetero Diels-Alder reactions proceeded to afford the corresponding dihydropyran-4-ones with high performance and high enantioselectivities. The reaction with aromatic aldehydes substituted by a coordinating group at the ortho position proceeded more smoothly.

Highly efficient enantioselective synthesis of optically active dihydropyrones by chiral titanium (iv) (5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol) complexes

The asymmetric hetero-Diels-Alder reaction of Danishefsky's diene and an aldehyde catalyzed by 20 mol% chiral H8-BINOL-Ti(IV) affords the corresponding 2-substitutent-2,3-dihydro-4H-pyran-4-one with ees of up to 99% under mild reaction conditio