33382-70-6Relevant articles and documents
Mannich Synthesis of Acetylenic Amino Alcohols in Aqueous Ionic Liquids
Simirskaya, Nina I.,Ignat'Ev, Nikolai V.,Schulte, Michael,Zlotin, Sergei G.
, p. 317 - 319 (2012)
Terminal alkynols react with formaldehyde and secondary amines in aqueous ionic liquid [emim]HSO-4 in the presence of Cu(OAc) to afford the corresponding 1-(a-hydroxyalkyl)- or 1-(b-hydroxyalkyl)-2- (aminomethyl)acetylenes in better yields in comparison with the reaction in conventional organic solvents. The catalytic system can be easily recovered and recycled.