33383-55-0

Usage

Uses

Used in Cosmetic Products:
(E)-trans-(+)-Chrysanthemumdicarboxylic acid is used as an active ingredient in cosmetic products for its safety profile, biodegradability, and biocompatibility. Its acidic properties and ability to form hydrogen bonds make it suitable for various formulations, such as creams, lotions, and serums.
Used in Skincare Industry:
In the skincare industry, (E)-trans-(+)-Chrysanthemumdicarboxylic acid is used as a skin conditioning agent for its ability to improve skin texture and hydration. Its acidic properties help regulate the skin's pH balance, promoting a healthy and radiant complexion.
Used in Hair Care Industry:
(E)-trans-(+)-Chrysanthemumdicarboxylic acid is used as a hair conditioning agent in hair care products, such as shampoos and conditioners. Its ability to form hydrogen bonds helps to improve hair manageability, reduce frizz, and enhance hair's overall appearance.
Used in Anti-aging Products:
In anti-aging products, (E)-trans-(+)-Chrysanthemumdicarboxylic acid is used as an active ingredient to help reduce the appearance of fine lines and wrinkles. Its ability to participate in biochemical reactions may contribute to the stimulation of collagen production, promoting skin elasticity and firmness.
Used in Sun Care Products:
(E)-trans-(+)-Chrysanthemumdicarboxylic acid is used as a UV filter in sun care products, providing protection against harmful UV rays. Its ability to form hydrogen bonds may also help to create a protective barrier on the skin, reducing the risk of sunburn and skin damage.

InChI:InChI=1/C10H14O4/c1-5(8(11)12)4-6-7(9(13)14)10(6,2)3/h4,6-7H,1-3H3,(H,11,12)(H,13,14)/b5-4+/t6-,7+/m0/s1

Upstream product

• 72079-86-8 methyl 4,6-O-(phenylmethylene)-2,3-dideoxy-2,3-C-isopropylidene-α-D-mannopyranoside 
• 623-73-4 diazoacetic acid ethyl ester 
• 42415-57-6 ethyl 2,5-dimethylhexa-2,4-dienoate2,5-dimethylsorbate 
• 72079-88-0 methyl 6,8-O-benzylidene-2,3,4,5-tetradeoxy-4,5-C-isopropylidene-2-C-methtyl-D-manno-oct-2-(E)-enoate 
• 72079-89-1 (E)-3-((1S,3R)-3-Formyl-2,2-dimethyl-cyclopropyl)-2-methyl-acrylic acid methyl ester 
• 92464-14-7 (E)-3-((1S,3S)-3-Formyl-2,2-dimethyl-cyclopropyl)-2-methyl-acrylic acid 
• 497-95-0 (+/-)-3t-(3t-carboxy-2,2-dimethyl-cycloprop-r-yl)-2-methyl-acrylic acid 
• 72079-87-9 4,6-O-benzylidene-2,3-dideoxy-2,3-C-isopropylidene-aldehydo-D-mannose 
• 92464-13-6 methyl (E)-2,3,4,5-tetradeoxy-4,5-C-isopropylidene-2-C-methyl-D-manno-oct-2-(E)-enoate 
• 92464-12-5 methyl 4,6-O-benzylidene-2,3-dideoxy-2,3-C--α-D-mannopyranoside 
• 72079-83-5 methyl 4,6-O-benzylidene-2,3-dideoxy-2,3-C--α-D-mannopyranoside 
• 72079-85-7 methyl 4,6-O-benzylidene-2,3-dideoxy-2,3-C--α-D-mannopyranoside 
• 72079-84-6 methyl 4,6-O-benzylidene-2,3-dideoxy-2,3-C--α-D-mannopyranoside 

Downstream Products

• 936-87-8 trans-caronic acid 
• 22467-83-0 (+/-)-3t-(3t-methoxycarbonyl-2,2-dimethyl-cycloprop-r-yl)-2-methyl-acrylic acid methyl ester 
• 936-87-8 (1S,2R)-3,3-Dimethyl-cyclopropane-1,2-dicarboxylic acid 

Relevant academic research and scientific papers

ANNULATED PYRANOSIDES-V. AN ENANTIOSPECIFIC ROUTE TO (+) AND (-) CHRYSANTHENUM DICARBOXYLIC ACIDS.

Methyl 2,3-anhydro-4,6-O-benzylidene-α-D-allopyranoside undergoes the Wadsworth-Emmons cyclopropanation with phosphonopropionate to give a cyclopropyl carboxylate which is processed to give the gem-dimethylcyclopropano pyranoside.The glycosylic acetal of this substance is readily hydrolyzed by boiling water, and the resulting cis-cyclopropane carboxaldehyde may epimerized quantitatively to the trans-analog by treatment with sodium methoxide.These are now converted into the (+)- and (-)-chrysanthenum dicarboxylic acids, respectively, by the same sequence of reactions involving (a) olefination with methyl 2-(triphenylphosphoranylidene)propionate, (b) hydrolysis of the benzylidene ring and cleavage of the resulting triol with sodium metaperiodate, and (c) oxidation of the resulting aldehyde with silver I oxide.In the case of the (+)-enantiomer the last reaction is preceeded by epimerization.The overall yields from the D-allopyranoside are respectively 27percent, in 10 steps for the (+)-enantiomer, and 24percent, in 10 steps for the (-)-enantiomer, from the known epoxide 7.