333971-05-4

Upstream product

• 1600-27-7 mercury(II) diacetate 
• 159581-87-0 RA-VII 
• 562834-33-7 C₄₁H₅₁N₇O₈S 
• 180850-29-7 [Tyr-6-Ψ(CS-NH)-D-Ala-1]RA-VII 
• 122621-60-7 RA-VII 
• 159581-88-1 [Tyr-3-Ψ(CS-NH)-Ala-4; Tyr-6-Ψ(CS-NH)-D-Ala-1]RA-VII 

Downstream Products

• 122621-60-7 RA-VII 

Relevant academic research and scientific papers

Synthesis of [L-Ala-1]RA-VII, [D-Ala-2]RA-VII, and [D-Ala-4]RA-VII by epimerization of RA-VII, an antitumor bicyclic hexapeptide from rubia plants, through oxazoles

Three epimers of a natural cyclic hexapeptide RA-VII were prepared via formation of oxazoles from thioamides or thioimidates of RA-VII followed by hydrolysis. They are the epimers at L-Ala-1, D-Ala-2, and D-Ala-4, respectively. The one having L-Ala-1 adop

A new approach to the epimeric analogue of cyclic peptides: Epimerisation via oxazoles of RA-VII, an anti-tumour bicyclic hexapeptide from Rubia plants

[D-Ala-4]RA-VII (9) and [D-Ala-2]RA-VII (10) were prepared from RA-VII (1), an anti-tumour bicyclic hexapeptide from Rubia plants, by conversion of its thioamide 3 into oxazoles 4 and 5 and subsequent acid-catalysed hydrolysis.