333971-06-5Relevant academic research and scientific papers
A new approach to the epimeric analogue of cyclic peptides: Epimerisation via oxazoles of RA-VII, an anti-tumour bicyclic hexapeptide from Rubia plants
Hitotsuyanagi, Yukio,Matsumoto, Yuji,Sasaki, Shin-ichi,Yamaguchi, Kentaro,Itokawa, Hideji,Takeya, Koichi
, p. 1535 - 1537 (2001)
[D-Ala-4]RA-VII (9) and [D-Ala-2]RA-VII (10) were prepared from RA-VII (1), an anti-tumour bicyclic hexapeptide from Rubia plants, by conversion of its thioamide 3 into oxazoles 4 and 5 and subsequent acid-catalysed hydrolysis.
