333985-60-7 Usage
Uses
Used in Pharmaceutical Research and Development:
4-(2,4-Difluorobenzyl)piperidine hydrochloride is utilized as a key building block for the synthesis of various biologically active molecules. Its unique structure, which includes the piperidine ring and the 2,4-difluorobenzyl group, contributes to the development of new drugs and bioactive compounds with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-(2,4-Difluorobenzyl)piperidine hydrochloride serves as a versatile intermediate for the creation of novel drug candidates. Its chemical properties allow for further functionalization and modification, enabling the design of molecules with specific biological targets and therapeutic effects.
Used in Drug Synthesis:
As a component in drug synthesis, 4-(2,4-Difluorobenzyl)piperidine hydrochloride is employed to construct complex molecular architectures. Its incorporation into drug molecules can potentially enhance pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, as well as improve pharmacodynamic effects, including potency and selectivity.
Used in Bioactive Compound Development:
4-(2,4-Difluorobenzyl)piperidine hydrochloride is also used in the development of bioactive compounds for various therapeutic areas. Its presence in these compounds can modulate biological activities, such as receptor binding, enzyme inhibition, or cellular signaling, leading to potential applications in treating diseases like cancer, neurological disorders, or infectious diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 333985-60-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,3,9,8 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 333985-60:
(8*3)+(7*3)+(6*3)+(5*9)+(4*8)+(3*5)+(2*6)+(1*0)=167
167 % 10 = 7
So 333985-60-7 is a valid CAS Registry Number.
333985-60-7Relevant academic research and scientific papers
Cyclic amine compounds as CCR5 antagonists
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, (2008/06/13)
A compound of formula (I) (wherein R1is a hydrogen atom, a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, R2is a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, or R1and R2may combine to each other together with A to form a heterocyclic group which may be substituted; A is N or N+—R5.Y?(R5is a hydrocarbon group; Y?is a counter anion); R3is a cyclic hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; n is 0 or 1; R4is a hydrogen atom, a hydrocarbon group which may be substituted, a heterocyclic group which may be substituted, an alkoxy group which may be substituted, an aryloxy group which may be substituted, or an amino group which may be substituted, E is a divalent aliphatic hydrocarbon group which may be substituted by group(s) other than oxo; G1is a bond, CO or SO2; G2is CO, SO2, NHCO, CONH or OCO; J is methine or a nitrogen atom; and each of Q and R is a bond or a divalent C1-3aliphatic hydrocarbon which may be substituted; provided that J is methine when G2is OCO, that one of Q and R is not a bond when the other is a bond and that each of Q and R is not substituted by oxo group(s) when G1is a bond) or a salt thereof has a potent CCR5 antagonistic activity and can be advantageously used for the treatment or prevention of infectious disease of various HIV in human (e.g. AIDS).
