333985-78-7

Usage

Uses

Used in Pharmaceutical Research:
DMCP is utilized as a reagent in pharmaceutical research for its capacity to inhibit acetylcholinesterase, an enzyme pivotal in the regulation of acetylcholine levels in the nervous system. This property makes it a potential agent for the treatment of neurological disorders such as Alzheimer's disease, where the inhibition of acetylcholinesterase can help slow cognitive decline.
Used in Organic Synthesis:
In the field of organic synthesis, DMCP is employed as a building block for the synthesis of other pharmaceutical compounds. Its versatile chemical structure allows it to be a useful intermediate in the production of various drugs, contributing to the development of new therapeutic agents.
Used in Drug Production:
As an indispensable intermediate in drug production, DMCP plays a crucial role in the manufacturing process of a wide range of pharmaceuticals. Its ability to be incorporated into the molecular structures of different drugs underscores its importance in the pharmaceutical industry, ensuring the availability of effective treatments for various health conditions.

Upstream product

• 1126-09-6 4-carbethoxypiperidine 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 

Downstream Products

• 333985-79-8 1-(dimethylcarbamoyl)piperidine-4-carboxylic acid 

Relevant academic research and scientific papers

THIAZOLE DERIVATIVE

(Wherein n is an integer of from 0 to 3; R1 is substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, a substituted or unsubstituted alicyclic heterocyclic group, or a substituted or unsubstituted aromatic heterocyclic grou

Cyclic amine compounds as CCR5 antagonists

A compound of formula (I) (wherein R1is a hydrogen atom, a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, R2is a hydrocarbon group which may be substituted, a non-aromatic heterocyclic group which may be substituted, or R1and R2may combine to each other together with A to form a heterocyclic group which may be substituted; A is N or N+—R5.Y?(R5is a hydrocarbon group; Y?is a counter anion); R3is a cyclic hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; n is 0 or 1; R4is a hydrogen atom, a hydrocarbon group which may be substituted, a heterocyclic group which may be substituted, an alkoxy group which may be substituted, an aryloxy group which may be substituted, or an amino group which may be substituted, E is a divalent aliphatic hydrocarbon group which may be substituted by group(s) other than oxo; G1is a bond, CO or SO2; G2is CO, SO2, NHCO, CONH or OCO; J is methine or a nitrogen atom; and each of Q and R is a bond or a divalent C1-3aliphatic hydrocarbon which may be substituted; provided that J is methine when G2is OCO, that one of Q and R is not a bond when the other is a bond and that each of Q and R is not substituted by oxo group(s) when G1is a bond) or a salt thereof has a potent CCR5 antagonistic activity and can be advantageously used for the treatment or prevention of infectious disease of various HIV in human (e.g. AIDS).