333986-05-3

Basic information

• Product Name: tert-butyl 4-(hydroxy(pyridin-2-yl)methyl)piperidine-1-carboxylate
• CAS NO: 333986-05-3
• Molecular Weight: 292.378
• Mol File: 333986-05-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-(hydroxy(pyridin-2-yl)methyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-(hydroxy(pyridin-2-yl)methyl)piperidine-1-carboxylate(333986-05-3)
• EPA Substance Registry System: tert-butyl 4-(hydroxy(pyridin-2-yl)methyl)piperidine-1-carboxylate(333986-05-3)

Safety Data

• Hazardous Substances Data: 333986-05-3(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 21970-13-8 (pyridin-2-yl)magnesium bromide 

Downstream Products

• 1167435-83-7 C₂₂H₂₆Cl₂N₂O₃ 
• 1167435-82-6 C₂₈H₃₂N₂O₃ 
• 1167435-87-1 C₂₂H₂₆Cl₂N₂O₃ 

Relevant articles and documents

OXIME COMPOUNDS USEFUL AS T CELL ACTIVATORS

Disclosed herein are oxime compounds having the structure of Formula (I):or a pharmaceutically acceptable salt, solvate, hydrate, isomer, tautomer, racemate, or isotope thereof, wherein R1, R2, R3, a, L, X, and Y are as defined herein. Pharmaceutical compositions comprising them, processes for preparing them and uses of them to treat or prevent diseases, disorders and conditions are also provided. The compounds are inhibitors of one or both of diacylglycerol kinase alpha (DGKα) and diacylglycerol kinase zeta (DGKζ) and are useful in the treatment of diseases, disorders and conditions related to DGKα and / or DGKζ activity. In particular, the compounds are useful for treating viral infections and proliferative disorders, such as cancer.

GLUCOKINASE ACTIVATORS

Provided are compounds of Formula I wherein R1, R2, Y, Z and G are as defined herein, that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes mellitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase.