334474-33-8

Upstream product

• 334474-30-5 5-[1-(4,4-dimethyl-5-methylsulfanyl-3,4-dihydropyrrol-2-ylidene)-phenyl-methyl]-3,4-dimethyl-1H-pyrrole-2-carbaldehyde 
• 18815-73-1 methylzinc iodide 
• 864682-34-8 3,4-dimethyl-5-[phenyl-(4,4,5-trimethyl-3,4-dihydro-pyrrol-2-ylidene)-methyl]-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 122-51-0 orthoformic acid triethyl ester 
• 887499-19-6 5-[(4,4-dimethyl-5-oxo-dihydro-furan-2-ylidene)-phenyl-methyl]-3,4-dimethyl-1H-pyrrole-2-carbaldehyde 
• 864681-96-9 5-[(4,4-dimethyl-5-oxo-dihydro-furan-2-ylidene)-phenyl-methyl]-3,4-dimethyl-1H-pyrrole-2-carboxylic acid tert-butyl ester 
• 887499-22-1 5-(4,4-dimethyl-2,5-dioxo-1-phenyl-hexyl)-3,4-dimethyl-1H-pyrrole-2-carbaldehyde 

Downstream Products

• 334474-36-1 Z-5-[1-(5-formyl-4,4-dimethyl-3,4-dihydropyrrol-2-ylidene)-phenyl-methyl]-3,4-dimethyl-1H-pyrrole-2-carbaldehyde 

Relevant academic research and scientific papers

Studies in chlorin chemistry. 3. A practical synthesis of C,D-ring symmetric chlorins of potential utility in photodynamic therapy

C,D-ring symmetric chlorins 8 were prepared in 47-85% yield, on scales up to several hundred milligrams, by condensation of appropriately substituted bis-formyldihydrodipyrrins 6 and dipyrromethane biscarboxylic acids 7 in 5% TFA/CH2Cl2/s

A new synthesis of chlorins

matrix presented A new synthesis of chlorins has been developed, based upon the acid-catalyzed condensation of dialdehydes AB with dipyrromethanes CD.