3345-86-6

Basic information

• Product Name: N-Phenylsulfamic acid
• Synonyms: N-Phenylsulfamic acid;Phenylsulfamidic acid
• CAS NO: 3345-86-6
• Molecular Formula: C₆H₇NO₃S
• Molecular Weight: 173.19
• Mol File: 3345-86-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Phenylsulfamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-Phenylsulfamic acid(3345-86-6)
• EPA Substance Registry System: N-Phenylsulfamic acid(3345-86-6)

Safety Data

• Hazardous Substances Data: 3345-86-6(Hazardous Substances Data)

Usage

Definition

ChEBI: A sulfamic acid having a phenyl group attached to nitrogen.

Upstream product

• 100-65-2 N-Phenylhydroxylamine 
• 60-29-7 diethyl ether 
• 625-01-4 ethyl chlorosulfate 
• 62-53-3 aniline 
• 2412-30-8 sulfuric acid monoisobutyl ester 
• 7791-25-5 sulfuryl dichloride 
• 56-23-5 tetrachloromethane 
• 7732-18-5 water 
• 127-68-4 sodium 3-nitrobenzenesulfonate 
• 64-17-5 ethanol 
• 98-95-3 nitrobenzene 
• 812-01-1 methyl chlorosulfate 
• 3147-53-3 2-hydroxy-5-phenylazo-benzoic acid 
• 5329-14-6 aminosulfonic acid 

Downstream Products

• 60260-49-3 phenylsulfamyl chloride 
• 7664-93-9 sulfuric acid 
• 62-53-3 aniline 
• 106881-36-1 ((3aR,5aS,8aS,8bR)-2,2,7,7-tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methyl phenylsulfamate 
• 121-57-3 4-aminobenzene sulfonic acid 
• 65104-19-0 N'-phenyl-hydrazidosulfuric acid ; sodium-salt 
• 45988-18-9 methyl-phenyl-amidosulfuric acid 
• 88-21-1 2-amino-1-benzenesulfonic acid 
• 732944-81-9 N-ethyl-N-phenylamidosulfate 

Relevant articles and documents

COMPOUNDS

A compound of formula (I), or a pharmaceutically acceptable salt thereof.

Indole, azaindole and related heterocyclic sulfonylureido piperazine derivatives

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with sulfonylureido piperazine derivatives of Formula I. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS. 1wherein: Z is 2Q is selected from the group consisting of: 3—W— is 4—represents a carbon-carbon bond or does not exist; and A is NR13R14.

Studies of Reactions of Amines with Sulfur Trioxide. VI. Thermal Reactions of Anilinium, Dimethylanilinium, and Trimethylanilinium Salts of Butylamidosulfuric Acid

When the title compounds were heated in an evacuated reaction vessel, both transsulfonation and rearrangement occurred.At lower temperatures (80-120 deg C) the corresponding phenylamidosulfates and sulfophenylamidosulfates (transsulfonation products) were the main products.Increasing temperature led to the formation of ring mono- and disulfonates (rearrangement products) at the expense of the transsulfonation products.The sulfonate group always migrated to the ortho and/or para position(s) to the amino group.In no case was any meta-product detected.There was no significant difference in the ease of transsulfonation among the anilinium salts studied exept 2,6-dimethyl- and 2,4,6-trimethylanilinium salts.On the other hand, the ease of rearrangement and the orientation of ring sulfonation depended strongly on the structure of the substrate anilines.The thermal reactions of 2,4,6-trimethylanilinium butylamidosulfate produced (2,4,6-trimethylphenylimido)bis(sulfate) in addition to (2,4,6-trimethylphenylamido)sulfate.This is the first isolation of an arylimidobis(sulfate) from such reactions.Mechanisms of the transsulfonation and rearrangement have been discussed.