334507-31-2

Basic information

• Product Name: 5-methyl-N-(4-methylphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
• CAS NO: 334507-31-2
• Molecular Weight: 239.28
• Mol File: 334507-31-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-methyl-N-(4-methylphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-N-(4-methylphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine(334507-31-2)
• EPA Substance Registry System: 5-methyl-N-(4-methylphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-7-amine(334507-31-2)

Safety Data

• Hazardous Substances Data: 334507-31-2(Hazardous Substances Data)

Upstream product

• 61-82-5 3-amino-1,2,4-triazole 
• 60728-85-0 3-oxo-N-p-tolyl-thiobutyramide 
• 24415-66-5 7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine 
• 106-49-0 p-toluidine 

Relevant articles and documents

DIHYDROOROTATE DEHYDROGENASE INHIBITORS WITH SELECTIVE ANTI-MALARIAL ACTIVITY

Compounds according to Formula (I), Formula (II), Formula (III), Formula (V), Formula (VI), or to Formula (VII), and pharmaceutical compositions of compounds that conform to Formula (IV) or (Formula VIII): where R1 through R33 are prescribed, selectively inhibit P. falciparum dihydroorotate dehydrogenase. Accordingly, a method for preventing and treating malaria attaches to such compounds, as well as to pharmaceutically acceptable salts, solvates, stereoisomers, tautomers, and prodrugs thereof.

Cyclocondensation of N-aryl-3-oxobutanethioamides with 1H-1,2,4-triazol-5- amine

Reactions of N-aryl-3-oxobutanethioamides with 1H-1,2,4-triazole-5-amine give mixtures of 7-arylamino-5-methyl[1,2,4]triazolo[1,5-a]pyrimidines, 5-methyl-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-7-thione, 7-methyl-4,5-dihydro[1,2,4]triazolo[1,5-a]pyrim