3346-68-7

Basic information

• Product Name: 5-Pyrimidinecarbonyl chloride, 1,2,3,4-tetrahydro-2,4-dioxo- (7CI,8CI,9CI)
• Synonyms: 5-Pyrimidinecarbonyl chloride, 1,2,3,4-tetrahydro-2,4-dioxo- (7CI,8CI,9CI);2,4-dioxo-1,2,3,4-tetrahydropyriMidine-5-carbonyl chloride;1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinecarbonyl chloride
• CAS NO: 3346-68-7
• Molecular Formula: C₅H₃ClN₂O₃
• Molecular Weight: 174.54192
• Product Categories: ACIDHALIDE
• Mol File: 3346-68-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.602±0.06 g/cm3(Predicted)
• PKA: 6.61±0.10(Predicted)
• CAS DataBase Reference: 5-Pyrimidinecarbonyl chloride, 1,2,3,4-tetrahydro-2,4-dioxo- (7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinecarbonyl chloride, 1,2,3,4-tetrahydro-2,4-dioxo- (7CI,8CI,9CI)(3346-68-7)
• EPA Substance Registry System: 5-Pyrimidinecarbonyl chloride, 1,2,3,4-tetrahydro-2,4-dioxo- (7CI,8CI,9CI)(3346-68-7)

Safety Data

• Hazardous Substances Data: 3346-68-7(Hazardous Substances Data)

Upstream product

• 23945-44-0 2,4-dihydroxypyrimidine-5-carboxylic acid 
• 23945-44-0 2,4-dihydroxypyrimidine-5-carboxylic acid 

Downstream Products

• 28485-17-8 5-carbethoxyuracil 
• 330784-47-9 avanafil 

Relevant articles and documents

Anti-tumor pyrimidine compounds and preparation method thereof

The invention belongs to the field of medicines and particularly relates to anti-tumor pyrimidine compounds and a preparation method thereof. The compounds belong to novel VEGFR (vascular endothelial growth factor receptor)-2 inhibitors and show good inhi

INHIBITORS OF JAK

The present invention is directed to compounds of formula (I) and tautomers and pharmaceutically acceptable salts thereof which are selective inhibitors of JAK. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK activity, and methods to prevent or treat a number of conditions mediated at least in part by JAK activity.

Herbicidally active substituted pyrimidine compounds and method of using same

Substituted pyrimidine compounds particularly useful as selective post-emergent herbicides are described for inhibiting the growth of and killing undesirable plants and weeds. The compounds hereof include 2,4-substituted pyrimidine-5-carboxylates having the general formula STR1 wherein X, Y and R represent specific types and classes of substituent groups. Especially preferred compounds in accordance with the invention include octyl 2,4-dichloropyrimidine-5-carboxylate, benzyl 2,4-dichloropyrimidine-5-carboxylate, allyl 2,4-dichloropyrimidine-5-carboxylate, ethyl 4-chloro-2-mercaptopyrimidine-5-carboxylate, butyl 2-chloro-4-di-n-propylaminopyrimidine-5-carboxylate. The compounds may be applied by conventional spray techniques at a dosage rate of from about 1/4 to 20 pounds per acre to good effect.