33465-18-8 Usage
General Description
(3S)-1,2,3,4,4a,9,10,10aα-Octahydro-1,1,4aβ-trimethyl-7-isopropyl-3α,6-phenanthrenediol, also known as 3-α-Hydroxy-7-β-isopropyl-5-α-cholan-24-oic acid, is a chemical compound with a complex molecular structure. It is a steroid derivative and a primary metabolite found in bile. (3S)-1,2,3,4,4a,9,10,10aα-Octahydro-1,1,4aβ-trimethyl-7-isopropyl-3α,6-phenanthrenediol is involved in the biosynthesis and metabolism of cholesterol in the liver. It is also a precursor for the synthesis of various steroid hormones in the body, such as cortisol and aldosterone. Additionally, it plays a crucial role in the digestion and absorption of dietary fats in the intestine, as it acts as an emulsifier to aid in the solubilization and uptake of lipids.
Check Digit Verification of cas no
The CAS Registry Mumber 33465-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,4,6 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 33465-18:
(7*3)+(6*3)+(5*4)+(4*6)+(3*5)+(2*1)+(1*8)=108
108 % 10 = 8
So 33465-18-8 is a valid CAS Registry Number.
33465-18-8Relevant articles and documents
Synthesis of (+)-Hinokiol, (+)-Hinokione, (+)-Salviol, and (+)-2-Oxoferruginol
Matsumoto, Takashi,Usui, Shuji,Kawashima, Hiroyuki,Mitsuki, Masanori
, p. 581 - 584 (2007/10/02)
Reduction of abieta-5,8,11,13-tetraen-3-one with lithium aluminium hydride afforded the corresponding alcohol, which was submitted to catalytic hydrogenation to yield abieta-8,11,13-trien-3β-ol (7) together with its 5βH-isomer.Acetylation of 7, followed by the Friedel-Crafts acylation, afforded 3β-acetoxy-12-acetylabieta-8,11,13-triene.This compound was converted into 3β,12-diacetoxyabieta-8,11,13-triene (11) by the Baeyer-Villiger oxidation.Treatment of 11 with lithium aluminium hydride yielded hinokiol, which was oxidized to hinokione.Subsequently, hinokiol was methylated and the resulting 12-methyl ether was dehydrated to afford 12-methoxyabieta-2,8,11,13-tetraene.The tetraene was then submitted to hydroboration-oxidation to give 12-methoxyabieta-8,11,13-trien-2α-ol (15) which, on demethylation with ethanethiol and anhydrous aluminium chloride, afforded salviol.Oxidation of 15 with pyridinium chlorochromate, followed by demethylation, gave 2-oxoferruginol.
