33469-12-4

Basic information

• Product Name: 1H-IMidazole, 2-(4-fluorophenyl)-5-(trifluoroMethyl)-
• Synonyms: 1H-IMidazole, 2-(4-fluorophenyl)-5-(trifluoroMethyl)-
• CAS NO: 33469-12-4
• Molecular Formula: C₁₀H₆F₄N₂
• Molecular Weight: 230.1616528
• Mol File: 33469-12-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-IMidazole, 2-(4-fluorophenyl)-5-(trifluoroMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-IMidazole, 2-(4-fluorophenyl)-5-(trifluoroMethyl)-(33469-12-4)
• EPA Substance Registry System: 1H-IMidazole, 2-(4-fluorophenyl)-5-(trifluoroMethyl)-(33469-12-4)

Safety Data

• Hazardous Substances Data: 33469-12-4(Hazardous Substances Data)

Usage

General Description

1H-Imidazole, 2-(4-fluorophenyl)-5-(trifluoromethyl) is a chemical compound that belongs to the imidazole class. It is characterized by a five-membered ring containing two nitrogen atoms. The presence of a fluorophenyl group and a trifluoromethyl group in its structure makes it a potentially important molecule in medicinal chemistry. These substituents can influence its pharmacological properties, such as its ability to interact with biological targets like enzymes or receptors. The compound's unique structure and properties make it a valuable building block for the synthesis of pharmaceuticals and agrochemicals.

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 431-67-4 1,1-dibromo-3,3,3-trifluoroacetone 

Downstream Products

• 1248744-95-7 methyl 2-(4-fluorophenyl)-1H-imidazole-5-carboxylate 
• 279251-17-1 2-(4-fluorophenyl)-1H-4-imidazolcarbaldehyde 
• 279250-94-1 2-(4-fluorophenyl)-4-cyano-1H-imidazole 

Relevant articles and documents

Discovery of novel 2-aryl-4-bis-amide imidazoles (ABAI) as anti-inflammatory agents for the treatment of inflammatory bowel diseases (IBD)

A series of 2-Aryl-4-Bis-amide Imidazoles (ABAI-1 to 30) were designed as anti-inflammatory agents. These compounds were synthesized and evaluated for the in vitro anti-inflammatory activities (inhibition of NO production and release of inflammatory cytok

Synthesis, structure, and neuroprotective properties of novel imidazolyl nitrones

A new series of imidazolyl nitrones spin traps has been synthesized and evaluated pharmacologically. The salient structural feature of these molecules is the presence of an imidazole moiety substituted by aromatic or heteroaromatic cycles. This connectivi

2-Pyrazinyl-trifluoromethylimidazoles and a method for their preparation

4(5)-Trifluoromethylimidazoles having optional substituents in the 1 and 2 positions are provided. The novel 4(5)-trifluoromethylimidazoles are prepared by reacting a 1,1-dihalo-3,3,3-trifluoroacetone compound with an appropriate carboxaldehyde and ammoni